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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: CARM1

Summary

GeneID

10498

Symbol

CARM1

Synonyms

PRMT4

Description

coactivator-associated arginine methyltransferase 1

Locus tag

Gene type

protein-coding

Map location

19p13.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Expression

P value: 1.485

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

SMAP2

0.92

0.90

AP000751.3

0.91

0.90

DLGAP1

0.91

0.90

NLK

0.90

C17orf51

0.90

KALRN

0.90

0.88

PIP4K2C

0.89

0.86

ABR

0.89

0.88

STXBP1

0.89

0.88

GAS7

0.89

0.88

Top 10 negatively co-expressed genes

DBI

-0.56

-0.64

AL139819.3

-0.53

-0.59

RAB34

-0.51

-0.58

RHOC

-0.50

-0.58

RAB13

-0.50

-0.58

NSBP1

-0.49

-0.58

AF347015.21

-0.49

-0.48

AP002478.3

-0.49

-0.56

EFEMP2

-0.47

-0.48

PHYHD1

-0.47

-0.50

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003713

transcription coactivator activity

ISS

GO:0005515

protein binding

ISS

GO:0016740

transferase activity

IEA

GO:0008276

protein methyltransferase activity

ISS

GO:0008469

histone-arginine N-methyltransferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

ISS

GO:0006350

transcription

IEA

GO:0008152

metabolic process

IEA

GO:0016568

chromatin modification

IEA

GO:0016571

histone methylation

ISS

GO:0044419

interspecies interaction between organisms

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IDA

15221992

GO:0005737

cytoplasm

IDA

15221992

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ELAVL1	ELAV1 \| HUR \| Hua \| MelG	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	-	HPRD	12237300
EP300	KAT3B \| p300	E1A binding protein p300	CARM1 interacts with p300.	BIND	15616592
NCOA3	ACTR \| AIB-1 \| AIB1 \| CAGH16 \| CTG26 \| KAT13B \| MGC141848 \| RAC3 \| SRC3 \| TNRC14 \| TNRC16 \| TRAM-1 \| pCIP	nuclear receptor coactivator 3	SRC-3 interacts with CARM1. This interaction was modelled on a demonstrated interaction between human SRC-3 and CARM1 from an unspecified species.	BIND	15383283
PABPN1	OPMD \| PAB2 \| PABP2	poly(A) binding protein, nuclear 1	Biochemical Activity	BioGRID	11850402
PRMT1	ANM1 \| HCP1 \| HRMT1L2 \| IR1B4	protein arginine methyltransferase 1	Phenotypic Enhancement	BioGRID	11050077
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	CARM1 interacts with p65.	BIND	15616592
SRCAP	DOMO1 \| EAF1 \| FLJ44499 \| KIAA0309 \| SWR1	Snf2-related CREBBP activator protein	-	HPRD	14500758
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	Reconstituted Complex	BioGRID	15186775
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	CARM1 interacts with p53. This interaction was modeled on a demonstrated interaction between mouse CARM1 and human p53.	BIND	15186775

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	432	438	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	432	438	m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-15/16/195/424/497	433	439	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-181	618	625	1A,m8	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-183	206	212	1A	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-223	16	22	1A	hsa-miR-223	UGUCAGUUUGUCAAAUACCCC
miR-26	615	621	1A	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	615	621	1A	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-493-5p	621	628	1A,m8	hsa-miR-493-5p	UUGUACAUGGUAGGCUUUCAUU
miR-9	596	602	m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.