Gene Page

Gene Page: CIB1

Summary

GeneID

10519

Symbol

CIB1

Synonyms

CIB|KIP|KIP1|SIP2-28

Description

calcium and integrin binding 1 (calmyrin)

Locus tag

Gene type

protein-coding

Map location

15q25.3-q26

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.2621

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

B3GALTL

0.66

0.32

GPR177

0.59

0.35

PODNL1

0.59

0.15

CBLN4

0.59

0.23

CBLN1

0.58

0.18

GLRA1

0.57

0.31

C20orf26

0.57

0.31

ACHE

0.57

0.24

MATN3

0.56

0.19

ZAP70

0.55

0.23

Top 10 negatively co-expressed genes

CXCL14

-0.22

-0.28

PLAC9

-0.19

-0.26

RERGL

-0.18

-0.25

C2orf82

-0.17

-0.24

AP000679.1

-0.17

-0.26

AC138647.1

-0.17

-0.20

WDR86

-0.17

-0.15

COX4I2

-0.17

-0.24

RLBP1

-0.17

-0.21

CA5A

-0.17

-0.23

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005509

calcium ion binding

IMP

15475008

GO:0005515

protein binding

IPI

15231747

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006302

double-strand break repair

TAS

9372844

GO:0007155

cell adhesion

TAS

9030514

GO:0006974

response to DNA damage stimulus

IDA

12011095

GO:0006915

apoptosis

IMP

10366599

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005654

nucleoplasm

IMP

10366599

GO:0005737

cytoplasm

IMP

10366599

GO:0005783

endoplasmic reticulum

IMP

10366599

GO:0016020

membrane

IDA

10366599

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
EXOSC10	PM-Scl \| PM/Scl-100 \| PMSCL \| PMSCL2 \| RRP6 \| Rrp6p \| p2 \| p3 \| p4	exosome component 10	-	HPRD,BioGRID	15231747
FEZ1	-	fasciculation and elongation protein zeta 1 (zygin I)	-	HPRD	11856312
ITGA2B	CD41 \| CD41B \| GP2B \| GPIIb \| GTA \| HPA3	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	-	HPRD	9030514
ITGB3	CD61 \| GP3A \| GPIIIa	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	-	HPRD,BioGRID	9030514
NBR1	1A1-3B \| KIAA0049 \| M17S2 \| MIG19	neighbor of BRCA1 gene 1	Two-hybrid	BioGRID	11856312
PLK2	SNK	polo-like kinase 2 (Drosophila)	-	HPRD,BioGRID	10523297 \|12651910
PLK3	CNK \| FNK \| PRK	polo-like kinase 3 (Drosophila)	-	HPRD,BioGRID	10523297 \|11039900
PRKDC	DNA-PKcs \| DNAPK \| DNPK1 \| HYRC \| HYRC1 \| XRCC7 \| p350	protein kinase, DNA-activated, catalytic polypeptide	-	HPRD,BioGRID	9372844
PSEN1	AD3 \| FAD \| PS1 \| S182	presenilin 1	Two-hybrid	BioGRID	10366599
PSEN2	AD3L \| AD4 \| PS2 \| STM2	presenilin 2 (Alzheimer disease 4)	-	HPRD,BioGRID	10366599
PTK2	FADK \| FAK \| FAK1 \| pp125FAK	PTK2 protein tyrosine kinase 2	-	HPRD,BioGRID	12881299
RAC3	-	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	-	HPRD,BioGRID	11756406
TERT	EST2 \| TCS1 \| TP2 \| TRT \| hEST2	telomerase reverse transcriptase	KIP interacts with hTERT.	BIND	15190070
UBR5	DD5 \| EDD \| EDD1 \| FLJ11310 \| HYD \| KIAA0896 \| MGC57263	ubiquitin protein ligase E3 component n-recognin 5	-	HPRD,BioGRID	12011095

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-214	48	54	1A	hsa-miR-214^brain	ACAGCAGGCACAGACAGGCAG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.