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| GeneID |
10540
|
| Symbol |
DCTN2
|
| Synonyms |
DCTN50|DYNAMITIN|RBP50
|
| Description |
dynactin 2 (p50) |
| See related |
HGNC:2712|MIM:607376|HPRD:09568| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
12q13.2-q13.3 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenics, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0861 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| |
| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| FBXL17 | 0.92 | 0.91 | | |
| COL4A3BP | 0.92 | 0.91 | | |
| PNMAL1 | 0.92 | 0.90 | | |
| DNAJC6 | 0.91 | 0.92 | | |
| MADD | 0.91 | 0.90 | | |
| PRKAR1A | 0.91 | 0.92 | | |
| VPS36 | 0.91 | 0.88 | | |
| YWHAB | 0.91 | 0.89 | | |
| BTRC | 0.91 | 0.90 | | |
| BTBD9 | 0.91 | 0.88 | | |
Top 10 negatively co-expressed genes | | AF347015.21 | -0.57 | -0.48 | | |
| EIF4EBP3 | -0.56 | -0.57 | | |
| C1orf61 | -0.55 | -0.66 | | |
| AP002478.3 | -0.54 | -0.56 | | |
| HIGD1B | -0.54 | -0.49 | | |
| FXYD1 | -0.54 | -0.47 | | |
| MT-CO2 | -0.54 | -0.49 | | |
| PLA2G5 | -0.53 | -0.46 | | |
| RAB34 | -0.53 | -0.59 | | |
| ACSF2 | -0.53 | -0.53 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0003774 | motor activity | IEA | | - |
| GO:0005515 | protein binding | IPI | | 10226031 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0007067 | mitosis | IMP | | 8647893 |
| GO:0008283 | cell proliferation | IMP | | 8647893 |
| GO:0007017 | microtubule-based process | IEA | | - |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0030426 | growth cone | IEA | axon, dendrite (GO term level: 5) | - |
| GO:0000776 | kinetochore | IDA | | 8647893 |
| GO:0005813 | centrosome | IDA | | 8647893 |
| GO:0005856 | cytoskeleton | IEA | | - |
| GO:0005869 | dynactin complex | IDA | | 8647893 |
| GO:0005874 | microtubule | IEA | | - |
| GO:0005737 | cytoplasm | IEA | | - |
| GO:0016020 | membrane | IEA | | - |
| GO:0030286 | dynein complex | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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