Gene Page

Gene Page: TACC2

Summary

GeneID

10579

Symbol

TACC2

Synonyms

AZU-1|ECTACC

Description

transforming, acidic coiled-coil containing protein 2

Locus tag

Gene type

protein-coding

Map location

10q26

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.03487

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IDA

15207008

GO:0035257

nuclear hormone receptor binding

IDA

15207008

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005813

centrosome

IEA

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	TACC2 interacts with CBP.	BIND	14767476
EP300	KAT3B \| p300	E1A binding protein p300	TACC2 interacts with p300.	BIND	14767476
HMG20B	BRAF25 \| BRAF35 \| FLJ26127 \| HMGX2 \| PP7706 \| SMARCE1r \| SOXL \| pp8857	high-mobility group 20B	Two-hybrid	BioGRID	16169070
KAT2A	GCN5 \| GCN5L2 \| MGC102791 \| PCAF-b \| hGCN5	K(lysine) acetyltransferase 2A	TACC2 interacts with hGCN5L2.	BIND	14767476
KAT2B	CAF \| P \| P/CAF \| PCAF	K(lysine) acetyltransferase 2B	TACC2 interacts with pCAF.	BIND	14767476
SMARCB1	BAF47 \| INI1 \| RDT \| SNF5 \| SNF5L1 \| Sfh1p \| Snr1 \| hSNFS	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	-	HPRD,BioGRID	12620397
YEATS4	4930573H17Rik \| B230215M10Rik \| GAS41 \| NUBI-1 \| YAF9	YEATS domain containing 4	-	HPRD,BioGRID	12620397

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	368	375	1A,m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	368	374	1A	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	368	374	1A	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-130/301	105	111	1A	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-217	148	155	1A,m8	hsa-miR-217	UACUGCAUCAGGAACUGAUUGGAU
miR-25/32/92/363/367	34	41	1A,m8	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-31	365	371	m8	hsa-miR-31	AGGCAAGAUGCUGGCAUAGCUG
miR-494	431	438	1A,m8	hsa-miR-494^brain	UGAAACAUACACGGGAAACCUCUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.