Gene Page: DRAP1

Summary
GeneID  10589
Symbol  DRAP1
Synonyms  NC2-alpha
Description  DR1-associated protein 1 (negative cofactor 2 alpha)
See related  HGNC:3019|MIM:602289|Ensembl:ENSG00000175550|HPRD:03796|
Locus tag  -
Gene type  protein-coding
Map location  11q13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0562 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZNF3820.840.85
TCERG10.820.84
ZNF8410.820.82
DOPEY10.820.81
PEX10.820.83
RBM50.810.85
ZNF4710.810.80
RBM60.810.80
RBBP60.810.83
KIAA17310.810.82
Top 10 negatively co-expressed genes
AF347015.31-0.65-0.74
MT-CO2-0.64-0.73
IFI27-0.63-0.73
AF347015.27-0.62-0.69
HIGD1B-0.61-0.73
MT-CYB-0.61-0.68
HSD17B14-0.60-0.70
AF347015.8-0.60-0.70
AF347015.21-0.60-0.77
METRN-0.60-0.73
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS8608938 
GO:0003714transcription corepressor activityTAS8608938 
GO:0043565sequence-specific DNA bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000122negative regulation of transcription from RNA polymerase II promoterTAS8608938 
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CDKN2CINK4C | p18 | p18-INK4Ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)Two-hybridBioGRID16169070 
DR1NC2 | NC2-BETAdown-regulator of transcription 1, TBP-binding (negative cofactor 2)-HPRD8608938 |8670811 
|8972183 |11461703 
Affinity Capture-Western
Reconstituted Complex		BioGRID8608938 |8972183 
FOXH1FAST-1 | FAST1forkhead box H1-HPRD,BioGRID12471260 
IRF1IRF-1 | MARinterferon regulatory factor 1DRAP1 interacts with IRF-1 promoter.BIND15893730 
NFYBCBF-A | CBF-B | HAP3 | NF-YBnuclear transcription factor Y, betaTwo-hybridBioGRID16189514 
PIK3R3DKFZp686P05226 | FLJ41892 | p55 | p55-GAMMAphosphoinositide-3-kinase, regulatory subunit 3 (gamma)Two-hybridBioGRID16189514 
POLE3CHARAC17 | CHRAC17 | YBL1 | p17polymerase (DNA directed), epsilon 3 (p17 subunit)Two-hybridBioGRID16189514 
TAF9AD-004 | AK6 | CGI-137 | CINAP | CIP | MGC1603 | MGC3647 | MGC5067 | MGC:1603 | MGC:3647 | MGC:5067 | TAF2G | TAFII31 | TAFII32 | TAFIID32TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDaTwo-hybridBioGRID16189514 
TAF9BDN-7 | DN7 | TAF9L | TAFII31L | TFIID-31TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDaTwo-hybridBioGRID16189514 
TBPGTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIIDTATA box binding protein-HPRD,BioGRID11461703 
TK1TK2thymidine kinase 1, solubleTwo-hybridBioGRID16169070 
TTF2HuF2transcription termination factor, RNA polymerase II-HPRD,BioGRID12927788 
HuF2 interacts with NC2.BIND12927788 
ZEB1AREB6 | BZP | DELTA-EF1 | MGC133261 | NIL-2-A | NIL-2A | NIL2A | TCF8 | ZEB | ZFHEP | ZFHX1Azinc finger E-box binding homeobox 1-HPRD,BioGRID9418848 
 


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