Gene Page

Gene Page: TRIM3

Summary

GeneID

10612

Symbol

TRIM3

Synonyms

BERP|FLJ16135|HAC1|RNF22|RNF97

Description

tripartite motif-containing 3

Locus tag

Gene type

protein-coding

Map location

11p15.5

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]

Click to show detail

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IEA

GO:0008270

zinc ion binding

IEA

GO:0008022

protein C-terminus binding

TAS

10391919

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007399

nervous system development

TAS

neurite (GO term level: 5)

10391919

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005737

cytoplasm

TAS

10391919

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACTN4	ACTININ-4 \| DKFZp686K23158 \| FSGS \| FSGS1	actinin, alpha 4	-	HPRD,BioGRID	10673389
MYO5A	GS1 \| MYH12 \| MYO5 \| MYR12	myosin VA (heavy chain 12, myoxin)	-	HPRD	10391919
TRIM3	BERP \| FLJ16135 \| HAC1 \| RNF22 \| RNF97	tripartite motif-containing 3	Two-hybrid	BioGRID	11331580
UBE2K	DKFZp564C1216 \| DKFZp686J24237 \| E2-25K \| HIP2 \| HYPG \| LIG	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	-	HPRD	11513855

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-130/301	158	164	m8	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-137	372	378	1A	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-142-5p	162	168	m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-148/152	91	97	1A	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-17-5p/20/93.mr/106/519.d	160	167	1A,m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-181	95	101	m8	hsa-miR-181a^brain	AACAUUCAACGCUGUCGGUGAGU
				hsa-miR-181b^SZ	AACAUUCAUUGCUGUCGGUGGG
				hsa-miR-181c^brain	AACAUUCAACCUGUCGGUGAGU
				hsa-miR-181d^brain	AACAUUCAUUGUUGUCGGUGGGUU
miR-330	181	187	m8	hsa-miR-330^brain	GCAAAGCACACGGCCUGCAGAGA
miR-362	216	222	m8	hsa-miR-362	AAUCCUUGGAACCUAGGUGUGAGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.