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| GeneID |
10863
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| Symbol |
ADAM28
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| Synonyms |
ADAM23|MDC-Lm|MDC-Ls|MDCL|eMDCII
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| Description |
ADAM metallopeptidase domain 28 |
| See related |
HGNC:206|MIM:606188|Ensembl:ENSG00000042980|HPRD:08391| |
| Locus tag |
- |
| Gene type |
protein-coding |
| Map location |
8p21.2 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_I | genome scan meta-analysis | Psr: 0.031 | | | GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.03086 | | | GSMA_IIE | genome scan meta-analysis (European-ancestry samples) | Psr: 0.00057 | | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
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| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| PRCC | 0.95 | 0.96 | | |
| FAM40A | 0.95 | 0.96 | | |
| GFOD2 | 0.95 | 0.96 | | |
| RNPS1 | 0.94 | 0.95 | | |
| PSMD3 | 0.94 | 0.94 | | |
| PJA1 | 0.94 | 0.94 | | |
| CHMP7 | 0.94 | 0.95 | | |
| UCK2 | 0.94 | 0.96 | | |
| DEDD | 0.94 | 0.93 | | |
| MKRN1 | 0.94 | 0.94 | | |
Top 10 negatively co-expressed genes | | AF347015.31 | -0.85 | -0.91 | | |
| MT-CO2 | -0.84 | -0.91 | | |
| AF347015.33 | -0.83 | -0.89 | | |
| AF347015.27 | -0.82 | -0.90 | | |
| MT-CYB | -0.81 | -0.89 | | |
| AF347015.8 | -0.80 | -0.90 | | |
| FXYD1 | -0.80 | -0.87 | | |
| S100B | -0.78 | -0.85 | | |
| TSC22D4 | -0.78 | -0.82 | | |
| AF347015.15 | -0.78 | -0.88 | | |
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| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004222 | metalloendopeptidase activity | IEA | | - |
| GO:0008270 | zinc ion binding | IEA | | - |
| GO:0008233 | peptidase activity | IEA | | - |
| GO:0046872 | metal ion binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006508 | proteolysis | IEA | | - |
| GO:0007283 | spermatogenesis | TAS | | 10587367 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
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| GO:0005576 | extracellular region | IEA | | - |
| GO:0016021 | integral to membrane | IEA | | - |
| GO:0005886 | plasma membrane | IEA | | - |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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