Gene Page: BRD8

Summary
GeneID  10902
Symbol  BRD8
Synonyms  SMAP|SMAP2|p120
Description  bromodomain containing 8
See related  HGNC:19874|MIM:602848|Ensembl:ENSG00000112983|HPRD:04166|
Locus tag  -
Gene type  protein-coding
Map location  5q31
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ZFYVE10.930.93
FAM161B0.910.92
VPS390.910.93
CSNK1D0.910.92
RNF2160.910.93
USP220.910.94
POGK0.910.94
FAM120B0.900.91
ADD10.900.93
EXOC70.900.91
Top 10 negatively co-expressed genes
AF347015.31-0.77-0.83
MT-CO2-0.76-0.83
AF347015.21-0.74-0.85
HIGD1B-0.73-0.81
IFI27-0.73-0.79
FXYD1-0.72-0.79
MT-CYB-0.71-0.77
AF347015.33-0.70-0.76
AF347015.8-0.70-0.79
AF347015.27-0.70-0.78
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004887thyroid hormone receptor activityTAS9368056 
GO:0003700transcription factor activityNAS8611617 
GO:0003706ligand-regulated transcription factor activityTAS9368056 
GO:0003713transcription coactivator activityTAS9368056 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001558regulation of cell growthIEA-
GO:0006357regulation of transcription from RNA polymerase II promoterTAS9368056 
GO:0006350transcriptionIEA-
GO:0007166cell surface receptor linked signal transductionTAS9368056 
GO:0016568chromatin modificationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusNAS8611617 
GO:0005730nucleolusIDA18029348 
GO:0005739mitochondrionIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
C20orf20Eaf7 | FLJ10914 | MRG15BP | MRGBP | URCC4chromosome 20 open reading frame 20-HPRD12963728 
JARID1AKDM5A | RBBP2 | RBP2jumonji, AT rich interactive domain 1ARBP2 interacts with BRD8 promoter.BIND15949438 
PPARGNR1C3 | PPARG1 | PPARG2 | PPARgammaperoxisome proliferator-activated receptor gamma-HPRD10517671 
RB1OSRC | RB | p105-Rb | pRb | pp110retinoblastoma 1pRB interacts with BRD8 promoter.BIND15949438 
RBL2FLJ26459 | P130 | Rb2retinoblastoma-like 2 (p130)p130 interacts with BRD8 promoter.BIND15949438 
RXRAFLJ00280 | FLJ00318 | FLJ16020 | FLJ16733 | MGC102720 | NR2B1retinoid X receptor, alphaReconstituted Complex
Two-hybrid		BioGRID10517671 
THRBERBA-BETA | ERBA2 | GRTH | MGC126109 | MGC126110 | NR1A2 | PRTH | THR1 | THRB1 | THRB2thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)Reconstituted Complex
Two-hybrid		BioGRID9368056 
 


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