Gene Page: GCN1L1

Summary
GeneID  10985
Symbol  GCN1L1
Synonyms  GCN1|GCN1L|KIAA0219
Description  GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
See related  HGNC:4199|MIM:605614|Ensembl:ENSG00000089154|HPRD:16127|
Locus tag  -
Gene type  protein-coding
Map location  12q24.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0156 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CDC70.620.63
WDR670.610.56
RNASEH2B0.610.56
C15orf230.600.62
CENPO0.600.57
GALNT10.590.60
RAD180.590.61
WDHD10.590.61
RYBP0.590.58
MYEF20.590.61
Top 10 negatively co-expressed genes
AF347015.31-0.50-0.56
MT-CYB-0.50-0.57
MT-CO2-0.49-0.57
AF347015.27-0.49-0.57
AF347015.8-0.48-0.56
AF347015.15-0.47-0.56
AF347015.33-0.47-0.54
AF347015.2-0.46-0.53
AF347015.26-0.45-0.53
AF347015.21-0.44-0.53
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI17353931 
GO:0008135translation factor activity, nucleic acid bindingNAS9234705 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006417regulation of translationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005840ribosomeNAS9234705 
GO:0005737cytoplasmNAS9234705 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BRF2BRFU | FLJ11052 | TFIIIB50BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-likeAffinity Capture-MSBioGRID17353931 
C20orf24PNAS-11 | RIP5chromosome 20 open reading frame 24Affinity Capture-MSBioGRID17353931 
CASP4ICE(rel)II | ICEREL-II | ICH-2 | Mih1/TX | TXcaspase 4, apoptosis-related cysteine peptidaseAffinity Capture-MSBioGRID17353931 
IKBKGAMCBX1 | FIP-3 | FIP3 | Fip3p | IKK-gamma | IP | IP1 | IP2 | IPD2 | NEMOinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma-HPRD14743216 
MAGEA6MAGE-3b | MAGE3B | MAGE6 | MGC52297melanoma antigen family A, 6Affinity Capture-MSBioGRID17353931 
MAGED1DLXIN-1 | NRAGEmelanoma antigen family D, 1Affinity Capture-MSBioGRID17353931 
MAST2FLJ39200 | KIAA0807 | MAST205 | MTSSK | RP4-533D7.1microtubule associated serine/threonine kinase 2Affinity Capture-MSBioGRID17353931 
MYCbHLHe39 | c-Mycv-myc myelocytomatosis viral oncogene homolog (avian)Affinity Capture-MSBioGRID17353931 
NEK6SID6-1512NIMA (never in mitosis gene a)-related kinase 6Affinity Capture-MSBioGRID17353931 
PTP4A3PRL-3 | PRL-R | PRL3protein tyrosine phosphatase type IVA, member 3Affinity Capture-MSBioGRID17353931 
RELAMGC131774 | NFKB3 | p65v-rel reticuloendotheliosis viral oncogene homolog A (avian)-HPRD14743216 
TNFRSF14ATAR | HVEA | HVEM | LIGHTR | TR2tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)Affinity Capture-MSBioGRID17353931 
TNFRSF1ACD120a | FPF | MGC19588 | TBP1 | TNF-R | TNF-R-I | TNF-R55 | TNFAR | TNFR1 | TNFR55 | TNFR60 | p55 | p55-R | p60tumor necrosis factor receptor superfamily, member 1A-HPRD14743216 
TNFRSF1BCD120b | TBPII | TNF-R-II | TNF-R75 | TNFBR | TNFR1B | TNFR2 | TNFR80 | p75 | p75TNFRtumor necrosis factor receptor superfamily, member 1B-HPRD14743216 
TSC22D1DKFZp686O19206 | MGC17597 | RP11-269C23.2 | TGFB1I4 | TSC22TSC22 domain family, member 1Affinity Capture-MSBioGRID17353931 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-124.11401461Ahsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-3305645701Ahsa-miR-330brainGCAAAGCACACGGCCUGCAGAGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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