Gene Page: SPINK5

Summary
GeneID  11005
Symbol  SPINK5
Synonyms  DKFZp686K19184|FLJ21544|FLJ97536|FLJ97596|FLJ99794|LEKTI|LETKI|NETS|NS|VAKTI
Description  serine peptidase inhibitor, Kazal type 5
See related  HGNC:15464|MIM:605010|Ensembl:ENSG00000133710|HPRD:05423|
Locus tag  -
Gene type  protein-coding
Map location  5q32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0032 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00459 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01718 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CDK40.870.75
GINS20.860.72
H2AFZ0.860.75
PCNA0.850.78
RANBP10.850.78
CLNS1A0.840.78
LRRC420.840.77
MCM50.840.75
RNASEH2A0.840.70
DTYMK0.840.70
Top 10 negatively co-expressed genes
AF347015.27-0.55-0.68
AF347015.31-0.52-0.64
MT-CO2-0.51-0.63
AF347015.8-0.51-0.64
AF347015.33-0.51-0.63
AF347015.15-0.51-0.66
MT-CYB-0.50-0.64
AF347015.2-0.49-0.67
PTH1R-0.49-0.59
AF347015.26-0.47-0.63
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004867serine-type endopeptidase inhibitor activityIDA10419450 |15680911 
GO:0004867serine-type endopeptidase inhibitor activityIEA-
GO:0008233peptidase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030855epithelial cell differentiationTAS12915442 
GO:0030155regulation of cell adhesionIEA-
GO:0016525negative regulation of angiogenesisTAS15680911 
GO:0035315hair cell differentiationTAS12915442 
GO:0042640anagenTAS12915442 
GO:0030198extracellular matrix organizationTAS15680911 
GO:0045580regulation of T cell differentiationTAS12915442 
GO:0045861negative regulation of proteolysisIEA-
GO:0050777negative regulation of immune responseTAS12915442 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIDA18029348 
GO:0005829cytosolIDA15680911 
GO:0005789endoplasmic reticulum membraneIDA15680911 
GO:0005576extracellular regionIDA15680911 
GO:0005576extracellular regionNAS10419450 
GO:0005737cytoplasmIDA12915442 |18029348 
GO:0005783endoplasmic reticulumIDA15680911 
GO:0005938cell cortexIDA12915442 
GO:0048471perinuclear region of cytoplasmIDA15680911 
GO:0042599lamellar bodyTAS15675955 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
PRSS1MGC120175 | MGC149362 | TRP1 | TRY1 | TRY4 | TRYP1protease, serine, 1 (trypsin 1)-HPRD10419450 
 


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