Gene Page: CHN1

Summary
GeneID  1123
Symbol  CHN1
Synonyms  ARHGAP2|CHN|DURS2|RHOGAP2
Description  chimerin (chimaerin) 1
See related  HGNC:1943|MIM:118423|Ensembl:ENSG00000128656|HPRD:00319|
Locus tag  -
Gene type  protein-coding
Map location  2q31.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0217 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FRMPD40.920.93
STXBP50.910.91
DOCK30.900.89
AP000751.30.890.86
LRRC8B0.880.87
SCN2A0.880.88
ZC3H12B0.880.86
UNC13A0.880.88
LMTK20.870.85
TLN20.870.84
Top 10 negatively co-expressed genes
RAB13-0.50-0.63
RAB34-0.48-0.54
PECI-0.47-0.50
DBI-0.46-0.53
IMPA2-0.46-0.54
RFXANK-0.44-0.46
ACAA2-0.44-0.48
C1orf61-0.43-0.57
ACSF2-0.43-0.49
PHYHD1-0.42-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005096GTPase activator activityIEA-
GO:0005070SH3/SH2 adaptor activityTAS8336731 
GO:0005515protein bindingIEA-
GO:0008270zinc ion bindingIEA-
GO:0019992diacylglycerol bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007242intracellular signaling cascadeIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GTF3C1DKFZp686A111 | TFIIIC | TFIIIC220 | TFIIICalphageneral transcription factor IIIC, polypeptide 1, alpha 220kDaTwo-hybridBioGRID16169070 
RAC1MGC111543 | MIG5 | TC-25 | p21-Rac1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-HPRD8496137 
RPS3AFTE1 | MFTL | MGC23240ribosomal protein S3ATwo-hybridBioGRID16169070 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-20536431A,m8hsa-miR-205UCCUUCAUUCCACCGGAGUCUG
hsa-miR-205UCCUUCAUUCCACCGGAGUCUG
miR-5434248m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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