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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: ZHX1

Summary

GeneID

11244

Symbol

ZHX1

Synonyms

Description

zinc fingers and homeoboxes 1

Locus tag

Gene type

protein-coding

Map location

8q24.13

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.1559

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IDA

12237128

GO:0005515

protein binding

IPI

10571058

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

GO:0043565

sequence-specific DNA binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0045892

negative regulation of transcription, DNA-dependent

IDA

12237128

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

IDA

12237128

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AKR1C3	DD3 \| DDX \| HA1753 \| HAKRB \| HAKRe \| HSD17B5 \| KIAA0119 \| hluPGFS	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	Two-hybrid	BioGRID	16169070
ATXN1	ATX1 \| D6S504E \| SCA1	ataxin 1	Two-hybrid	BioGRID	12659632
BARD1	-	BRCA1 associated RING domain 1	-	HPRD	15383276
BAT1	D6S81E \| DDX39B \| UAP56	HLA-B associated transcript 1	-	HPRD	14667819
BHLHB2	DEC1 \| SHARP-2 \| STRA13 \| Stra14 \| bHLHe40	basic helix-loop-helix domain containing, class B, 2	Two-hybrid	BioGRID	16169070
CHD3	Mi-2a \| Mi2-ALPHA \| ZFH	chromodomain helicase DNA binding protein 3	-	HPRD	15383276
CSNK2A1	CK2A1 \| CKII	casein kinase 2, alpha 1 polypeptide	Two-hybrid	BioGRID	16169070
DLST	DLTS	dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)	Two-hybrid	BioGRID	16169070
DYNLL1	DLC1 \| DLC8 \| DNCL1 \| DNCLC1 \| LC8 \| LC8a \| MGC126137 \| MGC126138 \| PIN \| hdlc1	dynein, light chain, LC8-type 1	Two-hybrid	BioGRID	16169070
EFNA2	ELF-1 \| EPLG6 \| HEK7-L \| LERK6	ephrin-A2	Two-hybrid	BioGRID	12659632
ELL	C19orf17 \| DKFZp434I1916 \| ELL1 \| Men	elongation factor RNA polymerase II	Two-hybrid	BioGRID	12659632
GNG11	GNGT11	guanine nucleotide binding protein (G protein), gamma 11	Two-hybrid	BioGRID	16169070
HSPE1	CPN10 \| GROES \| HSP10	heat shock 10kDa protein 1 (chaperonin 10)	Two-hybrid	BioGRID	16169070
IDH1	IDCD \| IDH \| IDP \| IDPC \| PICD	isocitrate dehydrogenase 1 (NADP+), soluble	Two-hybrid	BioGRID	16169070
LAMA4	DKFZp686D23145 \| LAMA3 \| LAMA4*-1	laminin, alpha 4	Two-hybrid	BioGRID	16169070
LYAR	FLJ20425 \| ZLYAR	Ly1 antibody reactive homolog (mouse)	Two-hybrid	BioGRID	16169070
MPHOSPH6	MPP \| MPP-6 \| MPP6	M-phase phosphoprotein 6	Two-hybrid	BioGRID	16169070
NACA	HSD48 \| MGC117224 \| NACA1	nascent polypeptide-associated complex alpha subunit	Two-hybrid	BioGRID	16169070
NFYA	CBF-A \| CBF-B \| FLJ11236 \| HAP2 \| NF-YA	nuclear transcription factor Y, alpha	NF-YA interacts with ZHX1. This interaction was modeled on a demonstrated interaction between NF-YA from an unspecified species and ZHX1 from human.	BIND	10571058
NFYA	CBF-A \| CBF-B \| FLJ11236 \| HAP2 \| NF-YA	nuclear transcription factor Y, alpha	-	HPRD,BioGRID	10441475 \|10571058
NP	FLJ94043 \| FLJ97288 \| FLJ97312 \| MGC117396 \| MGC125915 \| MGC125916 \| PNP \| PRO1837 \| PUNP	nucleoside phosphorylase	Two-hybrid	BioGRID	16169070
PAFAH1B3	-	platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa	Two-hybrid	BioGRID	16169070
PEX14	MGC12767 \| NAPP2 \| Pex14p \| dJ734G22.2	peroxisomal biogenesis factor 14	Two-hybrid	BioGRID	16169070
PIAS4	FLJ12419 \| MGC35296 \| PIASY \| Piasg \| ZMIZ6	protein inhibitor of activated STAT, 4	-	HPRD	15383276
PIGC	GPI2 \| MGC2049	phosphatidylinositol glycan anchor biosynthesis, class C	Two-hybrid	BioGRID	16169070
PRPF40A	FBP-11 \| FBP11 \| FLAF1 \| FLJ20585 \| FNBP3 \| HIP10 \| HYPA \| NY-REN-6	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	-	HPRD	15383276
PSMD11	MGC3844 \| Rpn6 \| S9 \| p44.5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	Two-hybrid	BioGRID	16169070
SAT1	DC21 \| KFSD \| SAT \| SSAT \| SSAT-1	spermidine/spermine N1-acetyltransferase 1	Two-hybrid	BioGRID	16169070
SERPINB9	CAP-3 \| CAP3 \| PI9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	Two-hybrid	BioGRID	16169070
TAL1	SCL \| TCL5 \| bHLHa17 \| tal-1	T-cell acute lymphocytic leukemia 1	-	HPRD	15383276
TALDO1	TAL \| TAL-H \| TALDOR \| TALH	transaldolase 1	-	HPRD	15383276
TARDBP	ALS10 \| TDP-43	TAR DNA binding protein	Two-hybrid	BioGRID	16169070
TERF1	FLJ41416 \| PIN2 \| TRBF1 \| TRF \| TRF1 \| hTRF1-AS \| t-TRF1	telomeric repeat binding factor (NIMA-interacting) 1	Two-hybrid	BioGRID	16169070
TNFRSF10C	CD263 \| DCR1 \| LIT \| MGC149501 \| MGC149502 \| TRAILR3 \| TRID	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	Two-hybrid	BioGRID	16169070
TOLLIP	FLJ33531 \| IL-1RAcPIP	toll interacting protein	Two-hybrid	BioGRID	16169070
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD	15383276
UTP3	CRL1 \| CRLZ1 \| FLJ23256 \| SAS10	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	Two-hybrid	BioGRID	16169070
WDR33	FLJ11294 \| WDC146	WD repeat domain 33	Two-hybrid	BioGRID	16169070
ZHX1	-	zinc fingers and homeoboxes 1	Reconstituted Complex Two-hybrid	BioGRID	12062805 \|12237128 \|12659632
ZHX2	AFR1 \| KIAA0854 \| RAF	zinc fingers and homeoboxes 2	-	HPRD	12741956
ZHX3	KIAA0395 \| TIX1	zinc fingers and homeoboxes 3	-	HPRD,BioGRID	12659632
ZMYND11	BRAM1 \| BS69 \| MGC111056 \| RP11-486H9.1	zinc finger, MYND domain containing 11	Two-hybrid	BioGRID	12659632
ZYX	ESP-2 \| HED-2	zyxin	Two-hybrid	BioGRID	12659632

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	1323	1329	m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
				hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
				hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
				hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-128	56	62	1A	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	56	62	1A	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-130/301	1491	1497	1A	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-132/212	1449	1455	1A	hsa-miR-212^SZ	UAACAGUCUCCAGUCACGGCC
miR-132/212	1449	1455	1A	hsa-miR-132^brain	UAACAGUCUACAGCCAUGGUCG
miR-15/16/195/424/497	1324	1330	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-182	157	163	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-186	395	401	m8	hsa-miR-186	CAAAGAAUUCUCCUUUUGGGCUU
miR-27	56	63	1A,m8	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	56	63	1A,m8	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-320	1364	1370	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-323	1586	1592	m8	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-335	1265	1271	m8	hsa-miR-335^brain	UCAAGAGCAAUAACGAAAAAUGU
miR-496	1476	1482	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-96	156	163	1A,m8	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.