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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: DTX2

Summary

GeneID

113878

Symbol

DTX2

Synonyms

KIAA1528|MGC71098|RNF58

Description

deltex homolog 2 (Drosophila)

Locus tag

Gene type

protein-coding

Map location

7q11.23

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0044

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

16189514

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007219

Notch signaling pathway

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DTX1	hDx-1	deltex homolog 1 (Drosophila)	-	HPRD	11226752
DTX2	KIAA1528 \| MGC71098 \| RNF58	deltex homolog 2 (Drosophila)	-	HPRD	11226752
DTX3	FLJ34766 \| MGC138863 \| MGC138864 \| RNF154	deltex 3 homolog (Drosophila)	-	HPRD	11226752
FREQ	DKFZp761L1223 \| FLUP \| NCS-1 \| NCS1	frequenin homolog (Drosophila)	Two-hybrid	BioGRID	16189514
HPCAL1	BDR1 \| HLP2 \| VILIP-3	hippocalcin-like 1	Two-hybrid	BioGRID	16189514
HPCAL4	DKFZp761G122 \| HLP4	hippocalcin like 4	Two-hybrid	BioGRID	16189514
NCALD	MGC33870 \| MGC74858	neurocalcin delta	Two-hybrid	BioGRID	16189514
NOTCH1	TAN1 \| hN1	Notch homolog 1, translocation-associated (Drosophila)	-	HPRD	11226752
PLSCR1	MMTRA1B	phospholipid scramblase 1	Two-hybrid	BioGRID	16189514
RBPMS	HERMES	RNA binding protein with multiple splicing	Two-hybrid	BioGRID	16189514
RFX6	MGC33442 \| RFXDC1 \| dJ955L16.1	regulatory factor X, 6	Two-hybrid	BioGRID	16189514
RHOXF2	PEPP-2 \| PEPP2 \| THG1	Rhox homeobox family, member 2	Two-hybrid	BioGRID	16189514
SFN	YWHAS	stratifin	Affinity Capture-MS	BioGRID	15778465
TRIP13	16E1BP	thyroid hormone receptor interactor 13	Two-hybrid	BioGRID	16189514
UBE2D4	HBUCE1	ubiquitin-conjugating enzyme E2D 4 (putative)	Affinity Capture-Western Two-hybrid	BioGRID	16189514
VSNL1	HLP3 \| HPCAL3 \| HUVISL1 \| VILIP \| VILIP-1	visinin-like 1	Two-hybrid	BioGRID	16189514

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	352	358	1A	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
				hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-25/32/92/363/367	367	373	1A	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.