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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: PLK3

Summary

GeneID

1263

Symbol

PLK3

Synonyms

CNK|FNK|PRK

Description

polo-like kinase 3 (Drosophila)

Locus tag

RP11-269F19.6

Gene type

protein-coding

Map location

1p34.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0385

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

ACSL4

0.90

0.93

SLC9A6

0.90

0.93

PAFAH1B1

0.89

0.91

PGM2L1

0.88

0.92

RABGAP1L

0.87

0.89

SRPK2

0.87

0.92

RAB11FIP2

0.87

0.90

SCN2A

0.86

0.89

BTRC

0.86

0.89

CLTC

0.86

0.91

Top 10 negatively co-expressed genes

EIF4EBP3

-0.59

-0.64

FXYD1

-0.57

RAB34

-0.57

-0.64

HIGD1B

-0.56

-0.59

ACSF2

-0.55

-0.59

MT-CO2

-0.55

-0.57

C11orf67

-0.55

-0.60

AP002478.3

-0.55

-0.61

AF347015.21

-0.54

AF347015.31

-0.54

-0.55

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0005515

protein binding

IEA

GO:0005524

ATP binding

IEA

GO:0004674

protein serine/threonine kinase activity

TAS

8702627

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006468

protein amino acid phosphorylation

TAS

8702627

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016020

membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CDC25C	CDC25	cell division cycle 25 homolog C (S. pombe)	-	HPRD,BioGRID	10557092\|11551930
CHEK2	CDS1 \| CHK2 \| HuCds1 \| LFS2 \| PP1425 \| RAD53	CHK2 checkpoint homolog (S. pombe)	-	HPRD,BioGRID	12242661
CIB1	CIB \| KIP \| KIP1 \| SIP2-28	calcium and integrin binding 1 (calmyrin)	-	HPRD,BioGRID	10523297 \|11039900
PTPRC	B220 \| CD45 \| CD45R \| GP180 \| LCA \| LY5 \| T200	protein tyrosine phosphatase, receptor type, C	Affinity Capture-Western	BioGRID	11551930
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	-	HPRD,BioGRID	11551930
TRIP13	16E1BP	thyroid hormone receptor interactor 13	Two-hybrid	BioGRID	16189514

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-125/351	116	122	1A	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	116	122	1A	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG
miR-133	119	125	m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	119	125	m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-24	187	193	m8	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG
miR-320	124	131	1A,m8	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.