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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: COL4A3

Summary

GeneID

1285

Symbol

COL4A3

Synonyms

Description

collagen, type IV, alpha 3 (Goodpasture antigen)

Locus tag

Gene type

protein-coding

Map location

2q36-q37

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.01016

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00916

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

AP1G2

0.82

0.81

COL11A2

0.81

0.84

AL117190.3

0.81

0.76

AL117190.4

0.78

0.73

SCNN1D

0.76

0.79

FBF1

0.75

0.74

MYO15B

0.74

0.88

MEG3

0.74

0.70

NPEPL1

0.73

0.72

FER1L4

0.73

0.71

Top 10 negatively co-expressed genes

CAPZA2

-0.39

-0.50

SUPT4H1

-0.36

-0.47

TPT1

-0.36

-0.54

BAG1

-0.35

-0.42

PSMA6

-0.35

-0.50

MOBKL3

-0.34

-0.43

RSL24D1

-0.34

-0.48

C1QBP

-0.33

-0.44

C3orf14

-0.33

-0.43

RPL36AL

-0.33

-0.41

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005178

integrin binding

IDA

12682293

GO:0005178

integrin binding

TAS

10766752

GO:0005515

protein binding

IPI

10212244 |12682293

GO:0005201

extracellular matrix structural constituent

IEA

GO:0008191

metalloendopeptidase inhibitor activity

NAS

10766752

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007155

cell adhesion

IEA

GO:0006917

induction of apoptosis

IDA

10766752

GO:0007166

cell surface receptor linked signal transduction

NAS

10766752

GO:0008285

negative regulation of cell proliferation

TAS

10837460

GO:0008015

blood circulation

TAS

10766752

GO:0007605

sensory perception of sound

TAS

7987396

GO:0006919

caspase activation

IDA

10766752

GO:0016525

negative regulation of angiogenesis

IDA

10766752 |12682293

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005576

extracellular region

IEA

GO:0005581

collagen

IEA

GO:0005587

collagen type IV

IDA

10766752

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ANTXR2	CMG-2 \| CMG2 \| FLJ31074 \| ISH \| JHF \| MGC111533 \| MGC45856	anthrax toxin receptor 2	-	HPRD	11683410
APP	AAA \| ABETA \| ABPP \| AD1 \| APPI \| CTFgamma \| CVAP \| PN2	amyloid beta (A4) precursor protein	-	HPRD	9136074
CD93	C1QR1 \| C1qR(P) \| C1qRP \| CDw93 \| MXRA4 \| dJ737E23.1	CD93 molecule	-	HPRD	1377218
COL4A3BP	CERT \| CERTL \| FLJ20597 \| GPBP \| STARD11	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	-	HPRD	10212244
DCN	CSCD \| DSPG2 \| PG40 \| PGII \| PGS2 \| SLRR1B	decorin	-	HPRD	10382266
FBLN2	-	fibulin 2	-	HPRD,BioGRID	7500359
FN1	CIG \| DKFZp686F10164 \| DKFZp686H0342 \| DKFZp686I1370 \| DKFZp686O13149 \| ED-B \| FINC \| FN \| FNZ \| GFND \| GFND2 \| LETS \| MSF	fibronectin 1	-	HPRD	3997552
HABP2	FSAP \| HABP \| HGFAL \| PHBP	hyaluronan binding protein 2	-	HPRD,BioGRID	1724753
MATN2	-	matrilin 2	-	HPRD	12180907
MFAP2	MAGP \| MAGP-1 \| MAGP1	microfibrillar-associated protein 2	-	HPRD,BioGRID	9278443
MMP9	CLG4B \| GELB \| MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	-	HPRD,BioGRID	9878537
OSM	MGC20461	oncostatin M	-	HPRD,BioGRID	11711546
SAA1	MGC111216 \| PIG4 \| SAA \| TP53I4	serum amyloid A1	-	HPRD	8995276
SERPINE2	GDN \| PI7 \| PN1 \| PNI	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	-	HPRD,BioGRID	8006028
TGFBI	BIGH3 \| CDB1 \| CDG2 \| CDGG1 \| CSD \| CSD1 \| CSD2 \| CSD3 \| EBMD \| LCD1	transforming growth factor, beta-induced, 68kDa	-	HPRD	11867580
USH2A	RP39 \| US2 \| USH2 \| USHERIN \| dJ1111A8.1	Usher syndrome 2A (autosomal recessive, mild)	-	HPRD	14676276

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	1129	1135	m8	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-135	2339	2346	1A,m8	hsa-miR-135a	UAUGGCUUUUUAUUCCUAUGUGA
miR-135	2339	2346	1A,m8	hsa-miR-135b	UAUGGCUUUUCAUUCCUAUGUG
miR-142-5p	796	802	m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-17-5p/20/93.mr/106/519.d	794	801	1A,m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-200bc/429	2595	2601	1A	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-208	1099	1105	1A	hsa-miR-208	AUAAGACGAGCAAAAAGCUUGU
miR-29	1600	1606	m8	hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
				hsa-miR-29a^SZ	UAGCACCAUCUGAAAUCGGUU
				hsa-miR-29b^SZ	UAGCACCAUUUGAAAUCAGUGUU
				hsa-miR-29c^SZ	UAGCACCAUUUGAAAUCGGU
miR-383	1239	1245	m8	hsa-miR-383^brain	AGAUCAGAAGGUGAUUGUGGCU
miR-499	1099	1105	1A	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.