Gene Page: COPA

Summary
GeneID  1314
Symbol  COPA
Synonyms  FLJ26320|HEP-COP
Description  coatomer protein complex, subunit alpha
See related  HGNC:2230|MIM:601924|Ensembl:ENSG00000122218|HPRD:03564|
Locus tag  -
Gene type  protein-coding
Map location  1q23-q25
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005179hormone activityIEA-
GO:0005509calcium ion bindingIEA-
GO:0005198structural molecule activityIEA-
GO:0051082unfolded protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006457protein foldingIEA-
GO:0016044membrane organizationEXP11031247 
GO:0006886intracellular protein transportIEA-
GO:0006890retrograde vesicle-mediated transport, Golgi to EREXP11031247 
GO:0016192vesicle-mediated transportIEA-
GO:0030157pancreatic juice secretionIDA1429581 
GO:0048205COPI coating of Golgi vesicleEXP16956762 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005792microsomeIDA9115636 
GO:0005794Golgi apparatusIEA-
GO:0005829cytosolEXP8533093 |8599108 
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceIDA1429581 
GO:0005625soluble fractionIDA9115636 
GO:0005737cytoplasmIDA9115636 
GO:0005783endoplasmic reticulumIEA-
GO:0030117membrane coatIEA-
GO:0016020membraneIEA-
GO:0031410cytoplasmic vesicleIEA-
GO:0030126COPI vesicle coatISS-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARCN1COPDarchain 1-HPRD8940050 
ARFGAP1ARF1GAP | HRIHFB2281 | MGC39924ADP-ribosylation factor GTPase activating protein 1-HPRD,BioGRID12379802 
BET1LBET1L1 | GOLIM3 | GS15 | HSPC197blocked early in transport 1 homolog (S. cerevisiae)-likeAffinity Capture-WesternBioGRID12388752 
COPB1COPB | DKFZp761K102 | FLJ10341coatomer protein complex, subunit beta 1Affinity Capture-Western
Two-hybrid		BioGRID8940050 |10921873 
COPB2beta'-COPcoatomer protein complex, subunit beta 2 (beta prime)Two-hybridBioGRID10921873 
-HPRD8537409 |8940050 
COPEFLJ13241 | epsilon-COPcoatomer protein complex, subunit epsilonAlpha-COP interacts with eta-COP. This interaction was modelled on a demonstrated interaction between rabbit alpha-COP and rabbit epsilon-COPBIND9482852 
-HPRD,BioGRID8858162 
PDGFRBCD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1platelet-derived growth factor receptor, beta polypeptide-HPRD,BioGRID9207175 
SACM1LDKFZp686A0231 | KIAA0851 | SAC1SAC1 suppressor of actin mutations 1-like (yeast)hSac1 interacts with alpha-COP.BIND14527956 
SLC25A11OGC | SLC20A4solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11Two-hybridBioGRID16169070 
STX8CARBsyntaxin 8-HPRD12388752 
 


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