Gene Page: COPB1

Summary
GeneID  1315
Symbol  COPB1
Synonyms  COPB|DKFZp761K102|FLJ10341
Description  coatomer protein complex, subunit beta 1
See related  HGNC:2231|MIM:600959|Ensembl:ENSG00000129083|HPRD:02981|
Locus tag  -
Gene type  protein-coding
Map location  11p15.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.6739 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI10199403 
GO:0005515protein bindingISS-
GO:0005198structural molecule activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016044membrane organizationEXP11031247 
GO:0006886intracellular protein transportIEA-
GO:0006890retrograde vesicle-mediated transport, Golgi to EREXP11031247 
GO:0006891intra-Golgi vesicle-mediated transportISS-
GO:0016192vesicle-mediated transportIEA-
GO:0048205COPI coating of Golgi vesicleEXP16956762 
GO:0044419interspecies interaction between organismsIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneTAS1840503 
GO:0005794Golgi apparatusIEA-
GO:0005798Golgi-associated vesicleTAS1840503 
GO:0005829cytosolEXP8533093 |8599108 
GO:0005829cytosolTAS1840503 
GO:0005737cytoplasmIEA-
GO:0030117membrane coatIEA-
GO:0016020membraneIEA-
GO:0031410cytoplasmic vesicleIEA-
GO:0030126COPI vesicle coatISS-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ADAM19FKSG34 | MADDAM | MLTNBADAM metallopeptidase domain 19 (meltrin beta)ADAM19 interacts with Beta-COP. This interaction was modeled on a demonstrated interaction between mouse ADAM19 and human beta-COP.BIND12463424 
-HPRD,BioGRID12463424 
ARCN1COPDarchain 1-HPRD,BioGRID8940050 
Beta-COP interacts with delta-COP. This interaction was modelled on a demonstrated interaction between rabbit beta-COP and rabbit delta-COP.BIND9482852 
ARF1-ADP-ribosylation factor 1-HPRD,BioGRID10720466 
COPAFLJ26320 | HEP-COPcoatomer protein complex, subunit alphaAffinity Capture-Western
Two-hybrid
BioGRID8940050 |10921873 
COPB2beta'-COPcoatomer protein complex, subunit beta 2 (beta prime)Affinity Capture-Western
Two-hybrid
BioGRID8940050 |10921873 
COPEFLJ13241 | epsilon-COPcoatomer protein complex, subunit epsilonAffinity Capture-WesternBioGRID8940050 
COPGCOPG1 | FLJ21068coatomer protein complex, subunit gamma-HPRD,BioGRID11056392 
COPG22-COP | DKFZp761N09121 | FLJ11781coatomer protein complex, subunit gamma 2-HPRD,BioGRID11409905 
HLA-AHLAAmajor histocompatibility complex, class I, AAffinity Capture-WesternBioGRID11884415 
HLA-GMHC-Gmajor histocompatibility complex, class I, G-HPRD,BioGRID12582157 
KCNK3K2p3.1 | OAT1 | TASK | TASK-1 | TBAK1potassium channel, subfamily K, member 3-HPRD,BioGRID12437930 
KDELR1ERD2 | ERD2.1 | HDEL | PM23KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1-HPRD,BioGRID11703931 
PDGFRBCD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1platelet-derived growth factor receptor, beta polypeptide-HPRD9207175 
PRKCEMGC125656 | MGC125657 | PKCE | nPKC-epsilonprotein kinase C, epsilon-HPRD11897493 
RGS2G0S8regulator of G-protein signaling 2, 24kDa-HPRD10982407 
RGS4DKFZp761F1924 | MGC2124 | MGC60244 | RGP4 | SCZD9regulator of G-protein signaling 4-HPRD10982407 
RHOQARHQ | RASL7A | TC10 | TC10Aras homolog gene family, member Q-HPRD12134073 
TAP1ABC17 | ABCB2 | APT1 | D6S114E | FLJ26666 | FLJ41500 | PSF1 | RING4 | TAP1*0102N | TAP1Ntransporter 1, ATP-binding cassette, sub-family B (MDR/TAP)Affinity Capture-WesternBioGRID11884415 
TAPBPNGS17 | TAPA | TPN | TPSN | tapasinTAP binding protein (tapasin)-HPRD,BioGRID11884415 
TRIM37KIAA0898 | MUL | POB1 | TEF3tripartite motif-containing 37Two-hybridBioGRID16189514 
USO1P115 | TAP | VDPUSO1 homolog, vesicle docking protein (yeast)-HPRD10903204 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4952772831Ahsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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