Gene Page: CRH

Summary
GeneID  1392
Symbol  CRH
Synonyms  CRF
Description  corticotropin releasing hormone
See related  HGNC:2355|MIM:122560|Ensembl:ENSG00000147571|HPRD:07172|
Locus tag  -
Gene type  protein-coding
Map location  8q13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.491 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005184neuropeptide hormone activityTASaxon, Synap, Brain, Neurotransmitter (GO term level: 6)7867564 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007268synaptic transmissionTASneuron, Synap, Neurotransmitter (GO term level: 6)7477348 
GO:0007165signal transductionTAS7867564 
GO:0007611learning or memoryTAS7477348 
GO:0007567parturitionTAS7585095 
GO:0007565female pregnancyTAS7585095 
GO:0006704glucocorticoid biosynthetic processIEA-
GO:0006954inflammatory responseIEA-
GO:0030325adrenal gland developmentIEA-
GO:0030324lung developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005625soluble fractionTAS7477348 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CRHR1CRF-R | CRF1 | CRFR1 | CRH-R1h | CRHR | CRHR1fcorticotropin releasing hormone receptor 1-HPRD,BioGRID9178757 
CRHR2CRFR2corticotropin releasing hormone receptor 2-HPRD,BioGRID8243338 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_LONG_TERM_DEPRESSION 7053All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS 8858All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS 12182All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
LI_AMPLIFIED_IN_LUNG_CANCER 178108All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
CHANG_IMMORTALIZED_BY_HPV31_UP 8455All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN 165106All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 210148All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-200bc/4295965m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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