Gene Page: CRYAB

Summary
GeneID  1410
Symbol  CRYAB
Synonyms  CRYA2|CTPP2|HSPB5
Description  crystallin, alpha B
See related  HGNC:2389|MIM:123590|Ensembl:ENSG00000109846|HPRD:00428|
Locus tag  -
Gene type  protein-coding
Map location  11q22.3-q23.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI16225851 
GO:0005212structural constituent of eye lensIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayNAS15609325 
GO:0006457protein foldingNAS9731540 
GO:0006936muscle contractionTAS9731540 
GO:0006916anti-apoptosisIDA14752512 
GO:0032387negative regulation of intracellular transportIDA14752512 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIDA14752512 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BAXBCL2L4BCL2-associated X proteinHalphaB-crystallin interacts with Bax.BIND14752512 
BCL2L1BCL-XL/S | BCL2L | BCLX | Bcl-X | DKFZp781P2092 | bcl-xL | bcl-xSBCL2-like 1HalphaB-crystallin interacts with Bcl-Xs.BIND14752512 
BMPR2BMPR-II | BMPR3 | BMR2 | BRK-3 | FLJ41585 | FLJ76945 | PPH1 | T-ALKbone morphogenetic protein receptor, type II (serine/threonine kinase)Affinity Capture-MSBioGRID15188402 
CRYAACRYA1 | HSPB4crystallin, alpha AAffinity Capture-Western
Two-hybrid
BioGRID11700327 
CRYABCRYA2 | CTPP2 | HSPB5crystallin, alpha BTwo-hybridBioGRID10625651 |11700327 
CRYBB2CCA2 | CRYB2 | CRYB2A | D22S665crystallin, beta B2Affinity Capture-Western
Two-hybrid
BioGRID11700327 
CRYGCCCL | CRYG3crystallin, gamma CAffinity Capture-Western
Two-hybrid
BioGRID11700327 
CS-citrate synthase-HPRD,BioGRID11377425 
HSPB1CMT2F | DKFZp586P1322 | HMN2B | HS.76067 | HSP27 | HSP28 | Hsp25 | SRP27heat shock 27kDa protein 1-HPRD,BioGRID1560006 |11700327 
HSPB2HSP27 | Hs.78846 | LOH11CR1K | MGC133245 | MKBPheat shock 27kDa protein 2Two-hybridBioGRID10625651 
PSMA3HC8 | MGC12306 | MGC32631 | PSC3proteasome (prosome, macropain) subunit, alpha type, 3-HPRD,BioGRID11341940 
 


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