Gene Page: CSTF2

Summary
GeneID  1478
Symbol  CSTF2
Synonyms  CstF-64
Description  cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
See related  HGNC:2484|MIM:600368|Ensembl:ENSG00000101811|HPRD:02652|
Locus tag  RP1-146H21.2
Gene type  protein-coding
Map location  Xq22.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0492 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SORBS30.600.59
SREBF10.580.56
KISS1R0.570.36
SOX80.570.42
FHOD10.560.38
AC020658.10.560.28
IL17D0.560.46
TMCO40.560.45
MMP280.550.58
LPIN30.550.44
Top 10 negatively co-expressed genes
FAM19A1-0.35-0.34
FBXW7-0.33-0.32
KIAA1239-0.32-0.31
PPEF1-0.31-0.32
AC106818.2-0.30-0.30
GTDC1-0.30-0.29
FAM19A2-0.29-0.30
R3HDM1-0.29-0.27
CDADC1-0.29-0.31
C1orf21-0.29-0.32
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003723RNA bindingTAS1741396 
GO:0005515protein bindingIPI11389848 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000398nuclear mRNA splicing, via spliceosomeEXP12226669 
GO:0006378mRNA polyadenylationTAS1741396 
GO:0006379mRNA cleavageTAS1741396 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusTAS1741396 
GO:0005730nucleolusIDA18029348 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BARD1-BRCA1 associated RING domain 1Affinity Capture-Western
Co-purification		BioGRID10477523 |11257228 
BAT3BAG-6 | BAG6 | D6S52E | G3HLA-B associated transcript 3Two-hybridBioGRID16169070 
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onsetAffinity Capture-Western
Co-purification		BioGRID10477523 |11257228 
C14orf1ERG28 | NET51chromosome 14 open reading frame 1Two-hybridBioGRID16169070 
CHD3Mi-2a | Mi2-ALPHA | ZFHchromodomain helicase DNA binding protein 3Two-hybridBioGRID16169070 
CPSF1CPSF160 | HSU37012 | P/cl.18cleavage and polyadenylation specific factor 1, 160kDaAffinity Capture-MSBioGRID10669729 
CPSF2CPSF100 | KIAA1367cleavage and polyadenylation specific factor 2, 100kDaAffinity Capture-MSBioGRID10669729 
CSTF1CstF-50 | CstFp50cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDaAffinity Capture-MSBioGRID10669729 
CSTF3CSTF-77 | MGC117398 | MGC43001 | MGC75122cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa-HPRD,BioGRID10669729 
DDX1DBP-RB | UKVH5dDEAD (Asp-Glu-Ala-Asp) box polypeptide 1-HPRD,BioGRID11598190 
ECH1HPXELenoyl Coenzyme A hydratase 1, peroxisomalTwo-hybridBioGRID16169070 
EEF1GEF1G | GIG35eukaryotic translation elongation factor 1 gammaTwo-hybridBioGRID16169070 
FEZ1-fasciculation and elongation protein zeta 1 (zygin I)Two-hybridBioGRID16169070 
IKBKAPDKFZp781H1425 | DYS | ELP1 | FD | FLJ12497 | IKAP | IKI3 | TOT1inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated proteinTwo-hybridBioGRID16169070 
IMMTDKFZp779P1653 | HMP | MGC111146 | P87 | P87/89 | P89 | PIG4 | PIG52inner membrane protein, mitochondrial (mitofilin)Two-hybridBioGRID16169070 
KAT5ESA1 | HTATIP | HTATIP1 | PLIP | TIP | TIP60 | cPLA2K(lysine) acetyltransferase 5Two-hybridBioGRID16169070 
KIAA1377-KIAA1377Two-hybridBioGRID16169070 
SUB1MGC102747 | P15 | PC4 | p14SUB1 homolog (S. cerevisiae)-HPRD,BioGRID11389848 
PC4 interacts with CSTF2 (CstF-64).BIND11389848 
SYMPKFLJ27092 | SPK | SYMsymplekin-HPRD,BioGRID10669729 
UBQLN1DA41 | DSK2 | FLJ90054 | PLIC-1 | XDRP1ubiquilin 1Two-hybridBioGRID16189514 
 


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