Gene Page: CYBA

Summary
GeneID  1535
Symbol  CYBA
Synonyms  p22-PHOX
Description  cytochrome b-245, alpha polypeptide
See related  HGNC:2577|MIM:608508|Ensembl:ENSG00000051523|HPRD:01989|
Locus tag  -
Gene type  protein-coding
Map location  16q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005506iron ion bindingIEA-
GO:0005515protein bindingIPI16326715 
GO:0020037heme bindingIEA-
GO:0017124SH3 domain bindingIPI7938008 
GO:0016175superoxide-generating NADPH oxidase activityIMP1763037 
GO:0009055electron carrier activityTAS2243141 
GO:0016491oxidoreductase activityIEA-
GO:0046872metal ion bindingIEA-
GO:0046982protein heterodimerization activityIPI12042318 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006810transportIEA-
GO:0006954inflammatory responseIMP2243141 
GO:0017004cytochrome complex assemblyIDA7938008 
GO:0014895smooth muscle hypertrophyISS-
GO:0042554superoxide releaseIMP2243141 
GO:0022900electron transport chainIEA-
GO:0045730respiratory burstIMP2243141 
GO:0050665hydrogen peroxide biosynthetic processISS-
GO:0045087innate immune responseIMP2243141 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0030141secretory granuleTAS12005167 
GO:0043020NADPH oxidase complexIDA3305576 
GO:0043020NADPH oxidase complexIMP1763037 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CYBBCGD | GP91-1 | GP91-PHOX | GP91PHOX | NOX2 | p91-PHOXcytochrome b-245, beta polypeptide-HPRD7938008 
NCF1FLJ79451 | NCF1A | NOXO2 | SH3PXD1A | p47phoxneutrophil cytosolic factor 1Reconstituted ComplexBioGRID7938008 
NCF1CSH3PXD1Cneutrophil cytosolic factor 1C pseudogene-HPRD7938008 
NCF2FLJ93058 | NCF-2 | NOXA2 | P67-PHOX | P67PHOXneutrophil cytosolic factor 2-HPRD,BioGRID7938008 |11733522 
|11917128 
NOX1GP91-2 | MOX1 | NOH-1 | NOH1NADPH oxidase 1Nox1 interacts with p22phox.BIND15322091 
RAC1MGC111543 | MIG5 | TC-25 | p21-Rac1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)-HPRD10486263 
 


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