Gene Page: DBN1

Summary
GeneID  1627
Symbol  DBN1
Synonyms  D0S117E|DKFZp434D064
Description  drebrin 1
See related  HGNC:2695|MIM:126660|Ensembl:ENSG00000113758|HPRD:00545|
Locus tag  -
Gene type  protein-coding
Map location  5q35.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 4 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CLSTN30.930.94
NFE2L10.930.91
RAB3A0.920.92
SV2A0.910.89
GRIN10.910.92
GPI0.910.90
PNPLA60.900.90
CLSTN10.900.92
ENO20.900.90
NDRG40.900.92
Top 10 negatively co-expressed genes
AF347015.21-0.55-0.38
GNG11-0.55-0.47
C1orf54-0.53-0.45
AP002478.3-0.52-0.46
C1orf61-0.51-0.48
AL050337.1-0.50-0.45
SYCP3-0.47-0.45
NOSTRIN-0.47-0.35
FAM159B-0.47-0.62
CLEC2B-0.47-0.35
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingNAS12761245 
GO:0005522profilin bindingISS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0048168regulation of neuronal synaptic plasticityNASneuron, Synap (GO term level: 9)12009525 
GO:0050773regulation of dendrite developmentNASneuron, dendrite (GO term level: 12)12009525 
GO:0007399nervous system developmentIEAneurite (GO term level: 5)-
GO:0007015actin filament organizationISS-
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0030425dendriteNASneuron, axon, dendrite (GO term level: 6)12009525 
GO:0005622intracellularIEA-
GO:0005737cytoplasmNAS12009525 
GO:0042641actomyosinNAS12761245 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DNMBPKIAA1010 | TUBAdynamin binding protein-HPRD,BioGRID14506234 
HOMER2ACPD | CPD | HOMER-2 | HOMER2A | HOMER2B | Vesl-2homer homolog 2 (Drosophila)-HPRD12676529 
IKBKGAMCBX1 | FIP-3 | FIP3 | Fip3p | IKK-gamma | IP | IP1 | IP2 | IPD2 | NEMOinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma-HPRD14743216 
MAP3K3MAPKKK3 | MEKK3mitogen-activated protein kinase kinase kinase 3-HPRD14743216 
RIPK3RIP3receptor-interacting serine-threonine kinase 3-HPRD14743216 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-19452458m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-2187637701A,m8hsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-320170176m8hsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-494400406m8hsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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