Gene Page: EID2
Summary ?
| GeneID | 163126 |
| Symbol | EID2 |
| Synonyms | CRI2|EID-2 |
| Description | EP300 interacting inhibitor of differentiation 2 |
| Reference | MIM:609773|HGNC:HGNC:28292|HPRD:16754| |
| Gene type | protein-coding |
| Map location | 19q13.2 |
| Pascal p-value | 0.007 |
| Sherlock p-value | 0.788 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0046332 | SMAD binding | IDA | 14612439 | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0007519 | skeletal muscle development | IEA | neuron (GO term level: 8) | - |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | - | |
| GO:0007183 | SMAD protein complex assembly | IDA | 14612439 | |
| GO:0007181 | transforming growth factor beta receptor complex assembly | IDA | 14612439 | |
| GO:0007275 | multicellular organismal development | IEA | - | |
| GO:0016481 | negative regulation of transcription | IDA | 14612439 | |
| GO:0030154 | cell differentiation | IEA | - | |
| GO:0042127 | regulation of cell proliferation | IDA | 14612439 | |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | IDA | 14612439 | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005622 | intracellular | IC | 14612439 | |
| GO:0005634 | nucleus | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| WANG CLIM2 TARGETS UP | 269 | 146 | All SZGR 2.0 genes in this pathway |
| LINDGREN BLADDER CANCER CLUSTER 3 UP | 329 | 196 | All SZGR 2.0 genes in this pathway |
| GAUSSMANN MLL AF4 FUSION TARGETS A UP | 191 | 128 | All SZGR 2.0 genes in this pathway |
| HEIDENBLAD AMPLIFIED IN PANCREATIC CANCER | 31 | 19 | All SZGR 2.0 genes in this pathway |
| KOYAMA SEMA3B TARGETS UP | 292 | 168 | All SZGR 2.0 genes in this pathway |
| DING LUNG CANCER EXPRESSION BY COPY NUMBER | 100 | 62 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
| IWANAGA CARCINOGENESIS BY KRAS PTEN DN | 353 | 226 | All SZGR 2.0 genes in this pathway |
| KUUSELO PANCREATIC CANCER 19Q13 AMPLIFICATION | 35 | 22 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA C CLUSTER DN | 32 | 21 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA C DN | 59 | 39 | All SZGR 2.0 genes in this pathway |
| BOYLAN MULTIPLE MYELOMA PCA3 UP | 80 | 54 | All SZGR 2.0 genes in this pathway |
| FORTSCHEGGER PHF8 TARGETS DN | 784 | 464 | All SZGR 2.0 genes in this pathway |