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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: DUSP1

Summary

GeneID

1843

Symbol

DUSP1

Synonyms

CL100|HVH1|MKP-1|MKP1|PTPN10

Description

dual specificity phosphatase 1

Locus tag

Gene type

protein-coding

Map location

5q34

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.0276

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

CSNK1G2

0.90

LRRC68

0.88

REXO1

0.87

0.88

RAB11FIP3

0.86

BRSK1

0.86

JPH3

0.85

0.86

MAP7D1

0.84

DMWD

0.84

0.85

SOLH

0.84

0.86

TBC1D17

0.84

0.82

Top 10 negatively co-expressed genes

GNG11

-0.55

-0.51

AF347015.21

-0.54

-0.39

C1orf54

-0.51

-0.44

CLEC2B

-0.49

-0.40

AL138743.2

-0.49

-0.40

AL050337.1

-0.48

-0.42

AF347015.31

-0.48

-0.36

NOSTRIN

-0.47

-0.40

SYCP3

-0.46

-0.43

MT-CO2

-0.46

-0.34

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

16286470

GO:0004726

non-membrane spanning protein tyrosine phosphatase activity

TAS

1406996

GO:0016787

hydrolase activity

IEA

GO:0017017

MAP kinase tyrosine/serine/threonine phosphatase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006470

protein amino acid dephosphorylation

IEA

GO:0007049

cell cycle

IEA

GO:0006979

response to oxidative stress

TAS

1406996

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
MAPK1	ERK \| ERK2 \| ERT1 \| MAPK2 \| P42MAPK \| PRKM1 \| PRKM2 \| p38 \| p40 \| p41 \| p41mapk	mitogen-activated protein kinase 1	-	HPRD,BioGRID	11278799
MAPK10	FLJ12099 \| FLJ33785 \| JNK3 \| JNK3A \| MGC50974 \| PRKM10 \| p493F12 \| p54bSAPK	mitogen-activated protein kinase 10	Affinity Capture-Western	BioGRID	11359773
MAPK12	ERK3 \| ERK6 \| P38GAMMA \| PRKM12 \| SAPK-3 \| SAPK3	mitogen-activated protein kinase 12	-	HPRD	11062068
MAPK14	CSBP1 \| CSBP2 \| CSPB1 \| EXIP \| Mxi2 \| PRKM14 \| PRKM15 \| RK \| SAPK2A \| p38 \| p38ALPHA	mitogen-activated protein kinase 14	-	HPRD	7535770
MAPK14		mitogen-activated protein kinase 14	Affinity Capture-Western Two-hybrid	BioGRID	11278799 \|11359773
MAPK3	ERK1 \| HS44KDAP \| HUMKER1A \| MGC20180 \| P44ERK1 \| P44MAPK \| PRKM3	mitogen-activated protein kinase 3	-	HPRD,BioGRID	11278799
MAPK8	JNK \| JNK1 \| JNK1A2 \| JNK21B1/2 \| PRKM8 \| SAPK1	mitogen-activated protein kinase 8	-	HPRD,BioGRID	11278799
MAPK9	JNK-55 \| JNK2 \| JNK2A \| JNK2ALPHA \| JNK2B \| JNK2BETA \| PRKM9 \| SAPK \| p54a \| p54aSAPK	mitogen-activated protein kinase 9	Affinity Capture-Western	BioGRID	11359773

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	433	439	1A	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-101	454	461	1A,m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-133	193	200	1A,m8	hsa-miR-133a	UUGGUCCCCUUCAACCAGCUGU
miR-133	193	200	1A,m8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-144	455	461	1A	hsa-miR-144	UACAGUAUAGAUGAUGUACUAG
miR-148/152	499	505	1A	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-200bc/429	327	334	1A,m8	hsa-miR-200b	UAAUACUGCCUGGUAAUGAUGAC
				hsa-miR-200c	UAAUACUGCCGGGUAAUGAUGG
				hsa-miR-429	UAAUACUGUCUGGUAAAACCGU
miR-495	608	614	1A	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.