Gene Page: DVL3

Summary
GeneID  1857
Symbol  DVL3
Synonyms  KIAA0208
Description  dishevelled, dsh homolog 3 (Drosophila)
See related  HGNC:3087|MIM:601368|Ensembl:ENSG00000161202|HPRD:03222|
Locus tag  -
Gene type  protein-coding
Map location  3q27
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 2.051 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.026 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CDC25B0.810.78
CDCA50.800.57
WDR51A0.780.56
CDC60.780.71
FAM83D0.780.42
POLA20.770.53
H2AFX0.760.49
CDC200.760.26
WDR620.760.65
TYMS0.760.42
Top 10 negatively co-expressed genes
CCDC80-0.28-0.27
CCBE1-0.27-0.18
AF347015.18-0.27-0.17
AF347015.21-0.26-0.11
ARHGAP15-0.25-0.22
IL32-0.25-0.24
AL391628.1-0.25-0.28
AF347015.26-0.25-0.06
AC010300.1-0.25-0.31
AF347015.8-0.24-0.08
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIEA-
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI15677333 |16189514 
GO:0016301kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)8817329 
GO:0016055Wnt receptor signaling pathwayIEA-
GO:0007242intracellular signaling cascadeIEA-
GO:0007507heart developmentTAS8817329 
GO:0007275multicellular organismal developmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AXIN1AXIN | MGC52315axin 1Affinity Capture-WesternBioGRID12805222 
BAHD1KIAA0945bromo adjacent homology domain containing 1Two-hybridBioGRID16189514 
CCNKCPR4 | MGC9113cyclin KTwo-hybridBioGRID16189514 
CSNK1DHCKIDcasein kinase 1, deltaTwo-hybridBioGRID16189514 
CSNK2A1CK2A1 | CKIIcasein kinase 2, alpha 1 polypeptide-HPRD,BioGRID10806215 
CTNNB1CTNNB | DKFZp686D02253 | FLJ25606 | FLJ37923catenin (cadherin-associated protein), beta 1, 88kDa-HPRD,BioGRID10806215 
DAB2DOC-2 | DOC2 | FLJ26626disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)-HPRD,BioGRID12805222 
DIDO1BYE1 | C20orf158 | DATF1 | DIDO2 | DIDO3 | DIO-1 | DIO1 | DKFZp434P1115 | FLJ11265 | KIAA0333 | MGC16140 | dJ885L7.8death inducer-obliterator 1Two-hybridBioGRID16189514 
DPPA2PESCRG1developmental pluripotency associated 2Two-hybridBioGRID16189514 
DVL1DVL | MGC54245dishevelled, dsh homolog 1 (Drosophila)-HPRD,BioGRID10330181 
KLHL12C3IP1 | DKIR | FLJ27152kelch-like 12 (Drosophila)Two-hybridBioGRID16189514 
LNX1LNX | MPDZ | PDZRN2ligand of numb-protein X 1Two-hybridBioGRID16189514 
MYST2HBO1 | HBOA | KAT7MYST histone acetyltransferase 2Two-hybridBioGRID16189514 
PITX1BFT | POTX | PTX1paired-like homeodomain 1Two-hybridBioGRID16189514 
PRPF3HPRP3 | HPRP3P | PRP3 | Prp3p | RP18PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)Affinity Capture-Western
Two-hybrid
BioGRID16189514 
SNX22FLJ13952sorting nexin 22Two-hybridBioGRID16189514 
TNFAIP8L1MGC17791tumor necrosis factor, alpha-induced protein 8-like 1Two-hybridBioGRID16189514 
VANGL1LPP2 | MGC5338 | STB2 | STBM2vang-like 1 (van gogh, Drosophila)-HPRD15456783 
ZBTB48HKR3 | ZNF855 | pp9964zinc finger and BTB domain containing 48Two-hybridBioGRID16189514 
ZNF408FLJ12827zinc finger protein 408Two-hybridBioGRID16189514 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-125/35111611167m8hsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
hsa-miR-125bbrainUCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrainUCCCUGAGACCCUUUAACCUGUG
miR-204/211951021A,m8hsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
miR-362915921m8hsa-miR-362AAUCCUUGGAACCUAGGUGUGAGU
miR-485-5p864870m8hsa-miR-485-5pAGAGGCUGGCCGUGAUGAAUUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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