Gene Page: NR0B1

Summary
GeneID  190
Symbol  NR0B1
Synonyms  AHC|AHCH|AHX|DAX-1|DAX1|DSS|GTD|HHG|NROB1
Description  nuclear receptor subfamily 0, group B, member 1
See related  HGNC:7960|MIM:300473|Ensembl:ENSG00000169297|HPRD:08362|
Locus tag  -
Gene type  protein-coding
Map location  Xp21.3-p21.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityIEA-
GO:0003706ligand-regulated transcription factor activityIDA7990953 
GO:0003707steroid hormone receptor activityIEA-
GO:0003714transcription corepressor activityIEA-
GO:0003723RNA bindingIDA10848616 
GO:0019904protein domain specific bindingIPI15100213 
GO:0042803protein homodimerization activityIPI16709599 
GO:0035258steroid hormone receptor bindingIPI11875111 
GO:0032448DNA hairpin bindingIDA9384387 
GO:0017163negative regulator of basal transcription activityIDA9384387 
GO:0043565sequence-specific DNA bindingIDA9384387 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0021854hypothalamus developmentNASBrain (GO term level: 10)15464421 
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA-
GO:0030238male sex determinationIEA-
GO:0007283spermatogenesisIEA-
GO:0006950response to stressIEA-
GO:0008104protein localizationIDA11875111 
GO:0006694steroid biosynthetic processIDA9384387 
GO:0033144negative regulation of steroid hormone receptor signaling pathwayIDA11875111 
GO:0033327Leydig cell differentiationIEA-
GO:0021983pituitary gland developmentNAS15464421 
GO:0030325adrenal gland developmentIMP7990953 
GO:0045596negative regulation of cell differentiationIEA-
GO:0060008Sertoli cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionIDA10848616 
GO:0005634nucleusIDA16709599 
GO:0005737cytoplasmIDA16709599 
GO:0042788polysomal ribosomeIDA10848616 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptor-HPRD,BioGRID11875111 
COPS2ALIEN | CSN2 | SGN2 | TRIP15COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)Reconstituted Complex
Two-hybrid		BioGRID10713076 
NR5A1AD4BP | ELP | FTZ1 | FTZF1 | SF-1 | SF1nuclear receptor subfamily 5, group A, member 1Reconstituted Complex
Two-hybrid		BioGRID11459805 |11713202 
NRIP1FLJ77253 | RIP140nuclear receptor interacting protein 1Reconstituted Complex
Two-hybrid		BioGRID11459805 
SREBF1SREBP-1c | SREBP1 | bHLHd1sterol regulatory element binding transcription factor 1Reconstituted Complex
Two-hybrid		BioGRID11713202 
 


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