Gene Page: EDNRA

Summary
GeneID  1909
Symbol  EDNRA
Synonyms  ETA|ETRA
Description  endothelin receptor type A
See related  HGNC:3179|MIM:131243|Ensembl:ENSG00000151617|HPRD:00571|
Locus tag  -
Gene type  protein-coding
Map location  4q31.23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0018 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0001599endothelin-A receptor activityNAS8611157 
GO:0004872receptor activityIEA-
GO:0005515protein bindingISS-
GO:0004435phosphoinositide phospholipase C activityTAS8702836 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001569patterning of blood vesselsIEA-
GO:0001666response to hypoxiaIEA-
GO:0001701in utero embryonic developmentIEA-
GO:0007202activation of phospholipase C activityTAS8702836 
GO:0007204elevation of cytosolic calcium ion concentrationTAS1849646 
GO:0007190activation of adenylate cyclase activityTAS8702836 
GO:0007186G-protein coupled receptor protein signaling pathwayNAS8611157 
GO:0007165signal transductionTAS1326535 
GO:0008283cell proliferationNAS9284755 
GO:0007507heart developmentIEA-
GO:0007585respiratory gaseous exchangeISS-
GO:0014032neural crest cell developmentIEA-
GO:0015758glucose transportISS-
GO:0006939smooth muscle contractionNAS9284755 
GO:0042310vasoconstrictionIEA-
GO:0030818negative regulation of cAMP biosynthetic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS1326535 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
EDN1ET1 | HDLCQ7endothelin 1-HPRD10770212 
EDN3ET3 | MGC15067 | MGC61498endothelin 3-HPRD11982704 
GNA11GNA-11guanine nucleotide binding protein (G protein), alpha 11 (Gq class)-HPRD,BioGRID10789830 
GNAI2GIP | GNAI2B | H_LUCA15.1 | H_LUCA16.1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2-HPRD,BioGRID7882989 
HDAC7DKFZp586J0917 | FLJ99588 | HD7A | HDAC7Ahistone deacetylase 7Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID11262386 
KAT5ESA1 | HTATIP | HTATIP1 | PLIP | TIP | TIP60 | cPLA2K(lysine) acetyltransferase 5Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID11262386 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-128133613421Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-200bc/429177917851Ahsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-2713361342m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-30-5p232123271Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
hsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-324-3p22932299m8hsa-miR-324-3pCCACUGCCCCAGGUGCUGCUGG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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