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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: EFNA4

Summary

GeneID

1945

Symbol

EFNA4

Synonyms

EFL4|EPLG4|LERK4|MGC125826

Description

ephrin-A4

Locus tag

Gene type

protein-coding

Map location

1q21-q22

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.0235

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.00814

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

EGR2

0.90

0.92

NR4A1

0.86

0.89

ADRB1

0.82

0.72

EGR3

0.81

0.80

MAST3

0.81

0.80

EGR4

0.80

0.86

ARC

0.80

0.81

CSRNP1

0.80

0.74

DUSP6

0.79

C2orf55

0.79

0.82

Top 10 negatively co-expressed genes

GTF3C6

-0.49

-0.59

BCL7C

-0.49

-0.68

RPL23A

-0.48

-0.67

C9orf46

-0.46

-0.61

DYNLT1

-0.45

-0.71

EXOSC8

-0.45

-0.57

TRAF4

-0.45

-0.60

TUBB2B

-0.45

-0.61

RBMX2

-0.44

-0.66

RPS19P3

-0.43

-0.68

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005005

transmembrane-ephrin receptor activity

TAS

8660976

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007267

cell-cell signaling

TAS

8660976

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005576

extracellular region

IEA

GO:0016020

membrane

IEA

GO:0005886

plasma membrane

IEA

GO:0005887

integral to plasma membrane

TAS

8660976

GO:0031225

anchored to membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
EPHA2	ECK	EPH receptor A2	-	HPRD	10607706
EPHA2	ECK	EPH receptor A2	-	HPRD	8755474 \|10607706
EPHA3	ETK \| ETK1 \| HEK \| HEK4 \| TYRO4	EPH receptor A3	Reconstituted Complex	BioGRID	9195962
EPHA4	HEK8 \| SEK \| TYRO1	EPH receptor A4	-	HPRD	10366629
EPHA5	CEK7 \| EHK1 \| HEK7 \| TYRO4	EPH receptor A5	The membrane bound ligand LERK4 interacts with the receptor EHK1. This interaction was modeled on a demonstrated interaction between LERK4 from human and EHK1 from rat.	BIND	8755474
EPHA6	DKFZp434C1418 \| EPA6 \| FLJ35246 \| PRO57066	EPH receptor A6	-	HPRD	10607706

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-340	279	285	1A	hsa-miR-340	UCCGUCUCAGUUACUUUAUAGCC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.