Gene Page: PIP5K3

Summary
GeneID  200576
Symbol  PIP5K3
Synonyms  CFD|FAB1|KIAA0981|MGC40423|PIKFYVE|PIP5K
Description  phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III
See related  HGNC:23785|MIM:609414|Ensembl:ENSG00000115020|HPRD:17852|
Locus tag  -
Gene type  protein-coding
Map location  2q33.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00916 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIEA-
GO:0005515protein bindingIPI17909029 
GO:0005524ATP bindingIEA-
GO:0016740transferase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:00163081-phosphatidylinositol-4-phosphate 5-kinase activityIEA-
GO:00163081-phosphatidylinositol-4-phosphate 5-kinase activityTAS15046600 
GO:0016301kinase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007242intracellular signaling cascadeIEA-
GO:0006898receptor-mediated endocytosisIMP14551253 
GO:0042147retrograde transport, endosome to GolgiIMP14551253 |16954148 
GO:0045184establishment of protein localizationIMP17909029 
GO:0044267cellular protein metabolic processIEA-
GO:0046488phosphatidylinositol metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005768endosomeIEA-
GO:0016020membraneIEA-
GO:0031901early endosome membraneIDA16448788 |16954148 
GO:0045121membrane raftIDA15046600 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
RABEPKDKFZp686P1077 | RAB9P40 | bA65N13.1 | p40Rab9 effector protein with kelch motifsAffinity Capture-Western
Biochemical Activity
Reconstituted Complex
Two-hybrid		BioGRID14530284 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101339634031A,m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-144339734031Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-200bc/42930573063m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-219314531511Ahsa-miR-219brainUGAUUGUCCAAACGCAAUUCU
miR-2245485541Ahsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
hsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-25/32/92/363/36730753081m8hsa-miR-25brainCAUUGCACUUGUCUCGGUCUGA
hsa-miR-32UAUUGCACAUUACUAAGUUGC
hsa-miR-92UAUUGCACUUGUCCCGGCCUG
hsa-miR-367AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZUAUUGCACUCGUCCCGGCCUC
miR-362150415111A,m8hsa-miR-362AAUCCUUGGAACCUAGGUGUGAGU
miR-369-3p312231291A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-37431233129m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-493-5p31903196m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-53933163322m8hsa-miR-539GGAGAAAUUAUCCUUGGUGUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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