SZGR2

Summary ?

GeneID	2015
Symbol	ADGRE1
Synonyms	EMR1\|TM7LN3
Description	adhesion G protein-coupled receptor E1
Reference	MIM:600493\|HGNC:HGNC:3336\|Ensembl:ENSG00000174837\|HPRD:02733\|Vega:OTTHUMG00000181966
Gene type	protein-coding
Map location	19p13.3

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
DNM:Fromer_2014	Whole Exome Sequencing analysis	This study reported a WES study of 623 schizophrenia trios, reporting DNMs using genomic DNA.

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
AC135048.1	0.77	0.78
ATG9A	0.76	0.76
PCYOX1L	0.76	0.77
ATP6AP1	0.76	0.79
CLSTN3	0.76	0.81
ENO2	0.76	0.76
GAD1	0.75	0.81
MGAT5B	0.75	0.79
TMEM179	0.75	0.76
PRMT8	0.75	0.79

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
AF347015.18	-0.47	-0.41
AF347015.21	-0.46	-0.33
AL139819.3	-0.44	-0.42
AF347015.26	-0.44	-0.32
AF347015.8	-0.42	-0.32
AF347015.2	-0.42	-0.29
AF347015.31	-0.41	-0.32
MT-CO2	-0.41	-0.31
MT-CYB	-0.41	-0.31
MT-ATP8	-0.40	-0.33

Section III. Gene Ontology annotation