Gene Page: FANCD2

Summary
GeneID  2177
Symbol  FANCD2
Synonyms  DKFZp762A223|FA-D2|FA4|FACD|FAD|FAD2|FANCD|FLJ23826
Description  Fanconi anemia, complementation group D2
See related  HGNC:3585|MIM:227646|Ensembl:ENSG00000144554|HPRD:01968|
Locus tag  -
Gene type  protein-coding
Map location  3p26
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.55 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MTA20.900.82
TRIM280.900.79
PATZ10.900.89
NUP1880.900.82
MAPK70.890.84
AAAS0.890.82
H3F3B0.880.84
MED120.880.84
PCIF10.880.79
SNRNP2000.880.81
Top 10 negatively co-expressed genes
C5orf53-0.66-0.75
CA4-0.62-0.72
CCNI2-0.59-0.66
HLA-F-0.59-0.60
FBXO2-0.59-0.58
ACOT13-0.59-0.68
PTH1R-0.59-0.58
AF347015.31-0.58-0.70
AF347015.27-0.58-0.69
CA11-0.58-0.71
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003674molecular_functionND-
GO:0005515protein bindingIPI12874027 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006281DNA repairIEA-
GO:0007049cell cycleIEA-
GO:0010332response to gamma radiationIDA12874027 
GO:0008150biological_processND-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
GO:0005634nucleusIEA-
GO:0005694chromosomeIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATMAT1 | ATA | ATC | ATD | ATDC | ATE | DKFZp781A0353 | MGC74674 | TEL1 | TELO1ataxia telangiectasia mutatedAffinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID12086603 |14499622 
BARD1-BRCA1 associated RING domain 1Co-localization
Reconstituted Complex		BioGRID12887909 
BLMBS | MGC126616 | MGC131618 | MGC131620 | RECQ2 | RECQL2 | RECQL3Bloom syndromeAffinity Capture-WesternBioGRID15257300 
BRCA1BRCAI | BRCC1 | IRIS | PSCP | RNF53breast cancer 1, early onsetCo-localization
Reconstituted Complex
Two-hybrid		BioGRID12887909 |14499622 
-HPRD11239454 
BRCA2BRCC2 | FACD | FAD | FAD1 | FANCB | FANCD | FANCD1breast cancer 2, early onsetAffinity Capture-Western
Co-localization
Two-hybrid		BioGRID15115758 |15199141 
FANCD2 interacts with BRCA2.BIND15115758 
FANCCFA3 | FAC | FACC | FLJ14675Fanconi anemia, complementation group C-HPRD11751423 
FANCEFACE | FAEFanconi anemia, complementation group E-HPRD,BioGRID12093742 
MEN1MEAI | SCG2multiple endocrine neoplasia IAffinity Capture-Western
Reconstituted Complex		BioGRID12874027 
NBNAT-V1 | AT-V2 | ATV | FLJ10155 | MGC87362 | NBS | NBS1 | P95nibrinAffinity Capture-WesternBioGRID12447395 
RAD51BRCC5 | HRAD51 | HsRad51 | HsT16930 | RAD51A | RECARAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)-HPRD12239151 
TNFRSF1ACD120a | FPF | MGC19588 | TBP1 | TNF-R | TNF-R-I | TNF-R55 | TNFAR | TNFR1 | TNFR55 | TNFR60 | p55 | p55-R | p60tumor necrosis factor receptor superfamily, member 1AAffinity Capture-MSBioGRID14743216 
TNFRSF1BCD120b | TBPII | TNF-R-II | TNF-R75 | TNFBR | TNFR1B | TNFR2 | TNFR80 | p75 | p75TNFRtumor necrosis factor receptor superfamily, member 1BAffinity Capture-MSBioGRID14743216 
UBA1A1S9 | A1S9T | A1ST | AMCX1 | GXP1 | MGC4781 | SMAX2 | UBA1A | UBE1 | UBE1Xubiquitin-like modifier activating enzyme 1Reconstituted ComplexBioGRID12887909 
UBE2D1E2(17)KB1 | SFT | UBC4/5 | UBCH5 | UBCH5Aubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)Reconstituted ComplexBioGRID12887909 
USP1UBPubiquitin specific peptidase 1USP1 interacts with FANCD2.BIND15694335 
 


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