Gene Page: FGB

Summary
GeneID  2244
Symbol  FGB
Synonyms  MGC104327|MGC120405
Description  fibrinogen beta chain
See related  HGNC:3662|MIM:134830|Ensembl:ENSG00000171564|HPRD:00620|
Locus tag  -
Gene type  protein-coding
Map location  4q28
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PRPS20.780.87
CDH100.780.80
LDB20.780.79
NDEL10.780.83
LRRC4C0.780.83
TMEM650.770.82
NDST30.770.82
TAPT10.770.77
L3MBTL40.760.76
PCDHAC20.760.84
Top 10 negatively co-expressed genes
AP002478.3-0.50-0.52
ACSF2-0.50-0.49
PHYHD1-0.49-0.51
MT-CO2-0.48-0.41
EIF4EBP3-0.48-0.51
AF347015.2-0.48-0.39
AF347015.21-0.48-0.38
HIGD1B-0.47-0.42
FXYD1-0.47-0.38
AF347015.26-0.47-0.37
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005102receptor bindingIEANeurotransmitter (GO term level: 4)-
GO:0030674protein binding, bridgingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionIEA-
GO:0030168platelet activationIEA-
GO:0051258protein polymerizationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP2742826 |5084810 |7356959 
|10605720 
GO:0005576extracellular regionNAS14718574 
GO:0005577fibrinogen complexTAS6688356 
GO:0005625soluble fractionTAS6688356 
GO:0005634nucleusIDA18029348 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIDA18029348 
GO:0005886plasma membraneEXP10605720 
GO:0005886plasma membraneIDA18029348 
GO:0031093platelet alpha granule lumenEXP5084810 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALRCRT | FLJ26680 | RO | SSA | cC1qRcalreticulin-HPRD,BioGRID7592883 
CDH57B4 | CD144 | FLJ17376cadherin 5, type 2 (vascular endothelium)B-beta(15-42) interacts with CDH5 (VE-cadherin).BIND15723073 
FBLN1FBLNfibulin 1-HPRD,BioGRID7642629 
FGAFib2 | MGC119422 | MGC119423 | MGC119425fibrinogen alpha chain-HPRD,BioGRID12356313 
FGG-fibrinogen gamma chain-HPRD,BioGRID12356313 
LPAAK38 | APOA | LPlipoprotein, Lp(a)-HPRD,BioGRID10980194 
NID1NIDnidogen 1-HPRD,BioGRID1680863 
SERPINA5PAI3 | PCI | PLANH3 | PROCIserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5-HPRD,BioGRID8148485 |8384496 
 


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