Gene Page: FHL1

Summary
GeneID  2273
Symbol  FHL1
Synonyms  FHL1B|FLH1A|KYO-T|MGC111107|SLIM1|XMPMA|bA535K18.1
Description  four and a half LIM domains 1
See related  HGNC:3702|MIM:300163|Ensembl:ENSG00000022267|HPRD:02157|
Locus tag  RP11-535K18.1
Gene type  protein-coding
Map location  Xq26
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0044 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DHFRL10.570.65
SGK10.560.58
KIAA10330.540.60
TMEM38B0.530.55
FBXL50.530.59
KLHL240.520.67
FRS20.520.62
ADIPOR20.520.58
ANGEL20.520.60
ZNF6640.520.59
Top 10 negatively co-expressed genes
CXCL14-0.36-0.47
AF347015.21-0.36-0.50
CLEC3B-0.35-0.44
CLDND2-0.34-0.39
IFI27L2-0.34-0.46
AC131097.1-0.33-0.45
ATP5I-0.33-0.39
AF347015.31-0.33-0.48
NOTUM-0.33-0.38
AL353354.3-0.33-0.25
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003674molecular_functionND-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0016049cell growthNAS-
GO:0009887organ morphogenesisNAS7626119 
GO:0007517muscle developmentNAS7626119 
GO:0007275multicellular organismal developmentIEA-
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005575cellular_componentND-
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CBX4NBP16 | PC2 | hPC2chromobox homolog 4 (Pc class homolog, Drosophila)KyoT1 interacts with HPC2. This interaction was modeled on a demonstrated interaction between KyoT1 from an unspecified species and human HPC2.BIND15710417 
FHL2AAG11 | DRAL | SLIM3four and a half LIM domains 2-HPRD,BioGRID12432079 
RBPJCBF1 | IGKJRB | IGKJRB1 | KBF2 | MGC61669 | RBP-J | RBPJK | RBPSUH | SUH | cslrecombination signal binding protein for immunoglobulin kappa J regionKyoT interacts with RBP-J. This interaction was modeled on a demonstrated interaction between KyoT and RBP-J, both from unspecified species.BIND15710417 
RING1RING1A | RNF1ring finger protein 1KyoT interacts with RING1. This interaction was modeled on a demonstrated interaction between KyoT from unspecified species and human RING1.BIND15710417 
SRFMCM1serum response factor (c-fos serum response element-binding transcription factor)SRF interacts with FHL1. This interaction was modeled on a demonstrated interaction between human SRF and FHL1 from an unspecified species.BIND15610731 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-200bc/4291401471A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-339410m8hsa-miR-339UCCCUGUCCUCCAGGAGCUCA
miR-4947097151Ahsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
miR-5442812871Ahsa-miR-544AUUCUGCAUUUUUAGCAAGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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