Gene Page: ATF6

Summary
GeneID  22926
Symbol  ATF6
Synonyms  ATF6A
Description  activating transcription factor 6
See related  HGNC:791|MIM:605537|Ensembl:ENSG00000118217|HPRD:16118|
Locus tag  -
Gene type  protein-coding
Map location  1q22-q23
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
OSBPL100.940.93
HERC30.910.94
FAM59A0.900.91
PLCL20.900.91
GUCY1A20.900.91
PPM1L0.900.92
STT3B0.900.91
ACVR1B0.890.91
RLBP1L10.890.89
WASF10.890.88
Top 10 negatively co-expressed genes
FXYD1-0.66-0.79
SERPINB6-0.66-0.69
HSD17B14-0.66-0.75
MT-CO2-0.64-0.78
AF347015.31-0.64-0.76
HIGD1B-0.63-0.76
AF347015.33-0.62-0.73
IFI27-0.62-0.74
AF347015.8-0.62-0.76
AF347015.27-0.62-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS9271374 |10564271 
GO:0003702RNA polymerase II transcription factor activityTAS9271374 
GO:0003713transcription coactivator activityTAS10866666 
GO:0043565sequence-specific DNA bindingIEA-
GO:0046983protein dimerization activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006357regulation of transcription from RNA polymerase II promoterTAS10564271 
GO:0006350transcriptionIEA-
GO:0006457protein foldingTAS10564271 
GO:0006990positive regulation of gene-specific transcription involved in unfolded protein responseTAS9837962 
GO:0006986response to unfolded proteinIEA-
GO:0007165signal transductionTAS9271374 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005789endoplasmic reticulum membraneTAS10564271 
GO:0005634nucleusTAS10564271 
GO:0005635nuclear envelopeTAS10866666 
GO:0005654nucleoplasmTAS10866666 
GO:0005783endoplasmic reticulumIEA-
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ATF6ATF6Aactivating transcription factor 6Two-hybridBioGRID11158310 
ATF6BCREB-RP | CREBL1 | FLJ10066 | G13activating transcription factor 6 betaTwo-hybridBioGRID11158310 
GTF2IBAP-135 | BAP135 | BTKAP1 | DIWS | FLJ38776 | FLJ56355 | IB291 | SPIN | TFII-I | WBS | WBSCR6general transcription factor II, iAffinity Capture-WesternBioGRID11287625 
NFYACBF-A | CBF-B | FLJ11236 | HAP2 | NF-YAnuclear transcription factor Y, alphaTwo-hybridBioGRID11158310 
NFYCCBF-C | CBFC | DKFZp667G242 | FLJ45775 | H1TF2A | HAP5 | HSM | NF-YCnuclear transcription factor Y, gammaReconstituted ComplexBioGRID11158310 
SRFMCM1serum response factor (c-fos serum response element-binding transcription factor)-HPRD,BioGRID9271374 
YY1DELTA | INO80S | NF-E1 | UCRBP | YIN-YANG-1YY1 transcription factor-HPRD,BioGRID10866666 
 


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