Gene Page

Gene Page: HABP4

Summary

GeneID

22927

Symbol

HABP4

Synonyms

IHABP4|Ki-1/57|MGC825|SERBP1L

Description

hyaluronan binding protein 4

Locus tag

RP11-172F4.4

Gene type

protein-coding

Map location

9q22.3-q31

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0838

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

MAP3K7

0.91

ELP3

0.91

0.89

DIS3

0.90

0.91

ZFP1

0.90

0.92

LEMD3

0.90

RAB14

0.90

ASH2L

0.90

0.87

BNIP3L

0.89

0.90

YTHDF3

0.89

0.90

USP15

0.89

0.91

Top 10 negatively co-expressed genes

FXYD1

-0.77

-0.81

MT-CO2

-0.76

-0.78

HIGD1B

-0.76

-0.81

AF347015.31

-0.74

-0.77

IFI27

-0.74

-0.80

AF347015.33

-0.72

-0.73

MT-CYB

-0.71

-0.74

AF347015.8

-0.70

-0.75

AC021016.1

-0.69

-0.74

AF347015.2

-0.69

-0.71

Gene Ontology

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0006350

transcription

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005737

cytoplasm

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CHD3	Mi-2a \| Mi2-ALPHA \| ZFH	chromodomain helicase DNA binding protein 3	-	HPRD,BioGRID	12505151
CHD3	Mi-2a \| Mi2-ALPHA \| ZFH	chromodomain helicase DNA binding protein 3	Ki-1/57 interacts with CHD-3.	BIND	12505151
ENO2	NSE	enolase 2 (gamma, neuronal)	Two-hybrid	BioGRID	16169070
GNB2L1	Gnb2-rs1 \| H12.3 \| HLC-7 \| PIG21 \| RACK1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	HABP4 (Ki-1/57) interacts with GNB2L1 (RACK1).	BIND	14699138
GNB2L1	Gnb2-rs1 \| H12.3 \| HLC-7 \| PIG21 \| RACK1		-	HPRD,BioGRID	14699138
PRKCA	AAG6 \| MGC129900 \| MGC129901 \| PKC-alpha \| PKCA \| PRKACA	protein kinase C, alpha	-	HPRD,BioGRID	14699138
PRKCB	MGC41878 \| PKC-beta \| PKCB \| PRKCB1 \| PRKCB2	protein kinase C, beta	-	HPRD	14699138
PRKCD	MAY1 \| MGC49908 \| PKCD \| nPKC-delta	protein kinase C, delta	-	HPRD	14699138
PRKCG	MGC57564 \| PKC-gamma \| PKCC \| PKCG \| SCA14	protein kinase C, gamma	-	HPRD	14699138
PRKCQ	MGC126514 \| MGC141919 \| PRKCT \| nPKC-theta	protein kinase C, theta	-	HPRD	14699138
PRKCZ	PKC-ZETA \| PKC2	protein kinase C, zeta	-	HPRD	14699138
PRMT1	ANM1 \| HCP1 \| HRMT1L2 \| IR1B4	protein arginine methyltransferase 1	Two-hybrid	BioGRID	16169070
VIM	FLJ36605	vimentin	Two-hybrid	BioGRID	16169070

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-130/301	126	132	m8	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	CAGUGCAAUAGUAUUGUCAAAGC
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
miR-17-5p/20/93.mr/106/519.d	128	134	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.