Gene Page: USP33

Summary
GeneID  23032
Symbol  USP33
Synonyms  KIAA1097|MGC16868|VDU1
Description  ubiquitin specific peptidase 33
See related  HGNC:20059|Ensembl:ENSG00000077254|HPRD:10297|
Locus tag  -
Gene type  protein-coding
Map location  1p31.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02692 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
FURIN0.910.92
CLCN70.910.91
HEATR7A0.910.91
MGAT30.900.92
KIF1A0.900.91
MEGF80.890.92
SBF10.890.89
CRTC10.890.90
TAOK20.890.89
MAPK8IP30.890.90
Top 10 negatively co-expressed genes
GNG11-0.68-0.67
C1orf54-0.67-0.66
AF347015.21-0.67-0.61
AL050337.1-0.63-0.65
SYCP3-0.63-0.64
CLEC2B-0.62-0.62
AF347015.31-0.62-0.55
AP002478.3-0.60-0.56
AL138743.2-0.60-0.55
SAT1-0.60-0.58
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI11739384 
GO:0005515protein bindingISS-
GO:0004221ubiquitin thiolesterase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0008234cysteine-type peptidase activityIEA-
GO:0008233peptidase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006511ubiquitin-dependent protein catabolic processTAS11739384 
GO:0016579protein deubiquitinationIDA11739384 
GO:0016579protein deubiquitinationISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmTAS11739384 
GO:0030891VCB complexTAS11739384 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DDX56DDX21 | DDX26 | NOH61DEAD (Asp-Glu-Ala-Asp) box polypeptide 56Two-hybridBioGRID16169070 
DIO25DII | D2 | SelY | TXDI2deiodinase, iodothyronine, type II-HPRD,BioGRID12865408 
EIF62 | CAB | EIF3A | ITGB4BP | b | b(2)gcn | gcn | p27BBPeukaryotic translation initiation factor 6Two-hybridBioGRID16169070 
TCEB1SIIItranscription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)-HPRD,BioGRID11739384 
TCEB2ELOB | SIIItranscription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)-HPRD11739384 
VHLHRCA1 | RCA1 | VHL1von Hippel-Lindau tumor suppressorpVHL interacts with VDU1-type II.BIND11739384 
-HPRD,BioGRID11739384 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1/2066874m8hsa-miR-1UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZUGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613AGGAAUGUUCCUUCUUUGCC
miR-130/301815821m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-148/152816822m8hsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
miR-1818698761A,m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-19814820m8hsa-miR-19aUGUGCAAAUCUAUGCAAAACUGA
hsa-miR-19bUGUGCAAAUCCAUGCAAAACUGA
miR-3651361431A,m8hsa-miR-365UAAUGCCCCUAAAAAUCCUUAU
miR-3787907961Ahsa-miR-378CUCCUGACUCCAGGUCCUGUGU
miR-409-3p6773m8hsa-miR-409-3pCGAAUGUUGCUCGGUGAACCCCU
miR-5439479531Ahsa-miR-543AAACAUUCGCGGUGCACUUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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