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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: GGA2

Summary

GeneID

23062

Symbol

GGA2

Synonyms

FLJ20966|KIAA1080|VEAR

Description

golgi associated, gamma adaptin ear containing, ARF binding protein 2

Locus tag

Gene type

protein-coding

Map location

16p12

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIE

genome scan meta-analysis (European-ancestry samples)

Psr: 0.01775

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

XPC

0.90

BMS1

0.90

0.89

INTS3

0.90

SUPT6H

0.90

0.89

DDX42

0.89

0.88

FLII

0.89

0.90

KIAA0556

0.89

0.90

TXLNA

0.89

0.90

RNF216

0.89

0.88

TUBGCP3

0.89

0.88

Top 10 negatively co-expressed genes

AF347015.21

-0.77

-0.79

AF347015.31

-0.75

-0.74

MT-CO2

-0.73

-0.72

IFI27

-0.72

-0.70

HIGD1B

-0.71

-0.72

C1orf54

-0.71

-0.75

VAMP5

-0.68

-0.69

AF347015.27

-0.68

-0.70

MT-CYB

-0.67

-0.66

FXYD1

-0.67

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

12505986

GO:0030306

ADP-ribosylation factor binding

IDA

10749927

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006886

intracellular protein transport

NAS

10749927

GO:0016192

vesicle-mediated transport

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005794

Golgi apparatus

IEA

GO:0005802

trans-Golgi network

IDA

10749927

GO:0005622

intracellular

IEA

GO:0005768

endosome

IEA

GO:0030117

membrane coat

IEA

GO:0016020

membrane

IEA

GO:0010008

endosome membrane

IEA

GO:0030131

clathrin adaptor complex

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AFTPH	FLJ20080 \| FLJ23793 \| MGC33965 \| Nbla10388	aftiphilin	-	HPRD	14665628
AP1GBP1	MGC104959 \| SYNG	AP1 gamma subunit binding protein 1	-	HPRD	10814529
AP1GBP1	MGC104959 \| SYNG	AP1 gamma subunit binding protein 1	-	HPRD	10747088 \|10814529
ARF1	-	ADP-ribosylation factor 1	-	HPRD	10747089
ARF3	-	ADP-ribosylation factor 3	-	HPRD,BioGRID	10749927
BACE1	ASP2 \| BACE \| FLJ90568 \| HSPC104 \| KIAA1149	beta-site APP-cleaving enzyme 1	-	HPRD	12135764
BACE2	AEPLC \| ALP56 \| ASP1 \| ASP21 \| BAE2 \| CDA13 \| CEAP1 \| DRAP	beta-site APP-cleaving enzyme 2	Protein-peptide Reconstituted Complex	BioGRID	12135764
CCDC91	DKFZp779L1558 \| FLJ11088 \| HSD8 \| p56	coiled-coil domain containing 91	-	HPRD	12808037
CLINT1	CLINT \| ENTH \| EPN4 \| EPNR \| EPSINR \| FLJ46753 \| KIAA0171	clathrin interactor 1	-	HPRD,BioGRID	12213833 \|12429846
CLTC	CHC \| CHC17 \| CLH-17 \| CLTCL2 \| Hc \| KIAA0034	clathrin, heavy chain (Hc)	-	HPRD,BioGRID	11301005 \|11387476
GGA2	FLJ20966 \| KIAA1080 \| VEAR	golgi associated, gamma adaptin ear containing, ARF binding protein 2	-	HPRD	12606052
IGF2R	CD222 \| CIMPR \| M6P-R \| MPR1 \| MPRI	insulin-like growth factor 2 receptor	-	HPRD	11387476
IGF2R	CD222 \| CIMPR \| M6P-R \| MPR1 \| MPRI	insulin-like growth factor 2 receptor	-	HPRD	11387475 \|11387476
M6PR	CD-MPR \| FLJ32994 \| MPR46 \| SMPR	mannose-6-phosphate receptor (cation dependent)	Two-hybrid	BioGRID	11387475
NECAP2	FLJ10420 \| RP4-798A10.1	NECAP endocytosis associated 2	Affinity Capture-Western	BioGRID	14665628
PIN1	DOD \| UBL5	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Two-hybrid	BioGRID	16189514
RAB5A	RAB5	RAB5A, member RAS oncogene family	Two-hybrid	BioGRID	14665628
RABEP1	RAB5EP \| RABPT5	rabaptin, RAB GTPase binding effector protein 1	-	HPRD,BioGRID	10747088 \|11387476 \|12505986
SORL1	C11orf32 \| FLJ21930 \| FLJ39258 \| LR11 \| LRP9 \| SORLA \| SorLA-1 \| gp250	sortilin-related receptor, L(DLR class) A repeats-containing	-	HPRD,BioGRID	11821067
SORT1	Gp95 \| NT3	sortilin 1	-	HPRD	11331584 \|11390366
SORT1	Gp95 \| NT3	sortilin 1	-	HPRD,BioGRID	11331584
SPG21	ACP33 \| BM-019 \| GL010 \| MASPARDIN \| MAST	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	Two-hybrid	BioGRID	16189514
TRIM23	ARD1 \| ARFD1 \| RNF46	tripartite motif-containing 23	Two-hybrid	BioGRID	16189514

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	665	671	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	395	401	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
				hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-125/351	442	449	1A,m8	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	442	449	1A,m8	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG
miR-204/211	455	461	m8	hsa-miR-204^brain	UUCCCUUUGUCAUCCUAUGCCU
miR-204/211	455	461	m8	hsa-miR-211	UUCCCUUUGUCAUCCUUCGCCU
miR-7	503	509	1A	hsa-miR-7^SZ	UGGAAGACUAGUGAUUUUGUUG
miR-96	90	96	m8	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.