Gene Page: FLG

Summary
GeneID  2312
Symbol  FLG
Synonyms  ATOD2
Description  filaggrin
See related  HGNC:3748|MIM:135940|Ensembl:ENSG00000143631|HPRD:15920|
Locus tag  -
Gene type  protein-coding
Map location  1q21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
OXT0.950.05
HCRT0.94-0.16
TMEM1900.94-0.19
AVP0.940.36
PMCH0.93-0.14
FAM81B0.910.19
C8orf120.910.45
WDR380.910.14
CCDC890.910.45
CAPSL0.900.40
Top 10 negatively co-expressed genes
TMEM81-0.22-0.71
DPF1-0.22-0.74
TNRC4-0.22-0.72
ARHGEF2-0.21-0.54
RTF1-0.21-0.73
ENOX1-0.21-0.73
CHD3-0.21-0.74
PCGF3-0.21-0.71
ELAVL3-0.21-0.74
ZNF589-0.21-0.74
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0005509calcium ion bindingTAS8417356 
GO:0005198structural molecule activityIEA-
GO:0005198structural molecule activityNAS2740331 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007275multicellular organismal developmentNAS2740331 
GO:0030154cell differentiationNAS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonNAS-
GO:0005882intermediate filamentNAS2740331 
GO:0016023cytoplasmic membrane-bounded vesicleIDA12850301 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CSNK2A1CK2A1 | CKIIcasein kinase 2, alpha 1 polypeptide-HPRD8270625 
LORMGC111513loricrinReconstituted ComplexBioGRID8999895 
PI3ESI | MGC13613 | SKALP | WAP3 | WFDC14 | cementoinpeptidase inhibitor 3, skin-derivedReconstituted ComplexBioGRID8999895 
 


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