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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

Gene Ranking Integration

Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: FLT4

Summary

GeneID

2324

Symbol

FLT4

Synonyms

FLT41|LMPH1A|PCL|VEGFR3

Description

fms-related tyrosine kinase 4

Locus tag

Gene type

protein-coding

Map location

5q35.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.0276

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0005021

vascular endothelial growth factor receptor activity

IDA

9012504

GO:0005021

vascular endothelial growth factor receptor activity

IEA

GO:0004872

receptor activity

IEA

GO:0005515

protein binding

IEA

GO:0005515

protein binding

IPI

16530705

GO:0005524

ATP binding

IEA

GO:0004713

protein tyrosine kinase activity

IEA

GO:0016740

transferase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

IEA

GO:0006468

protein amino acid phosphorylation

IEA

GO:0008284

positive regulation of cell proliferation

IEA

GO:0008284

positive regulation of cell proliferation

IGI

11574540

GO:0048010

vascular endothelial growth factor receptor signaling pathway

IDA

9012504

GO:0048010

vascular endothelial growth factor receptor signaling pathway

IGI

11574540

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IEA

GO:0005887

integral to plasma membrane

TAS

8386825

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
FIGF	VEGF-D \| VEGFD	c-fos induced growth factor (vascular endothelial growth factor D)	-	HPRD	9435229
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	-	HPRD,BioGRID	7675451 \|7970715 \|8662748 \|9927207
ITGB1	CD29 \| FNRB \| GPIIA \| MDF2 \| MSK12 \| VLA-BETA \| VLAB	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	-	HPRD,BioGRID	11553610
SHC1	FLJ26504 \| SHC \| SHCA	SHC (Src homology 2 domain containing) transforming protein 1	-	HPRD	7675451 \|8662748 \|9927207
SHC1	FLJ26504 \| SHC \| SHCA		Affinity Capture-Western Reconstituted Complex	BioGRID	7970715 \|8662748 \|9927207
VEGFC	Flt4-L \| VRP	vascular endothelial growth factor C	VEGF-C interacts with VEGFR-3. This interaction was modeled on a demonstrated interaction between human VEGF-C and VEGFR-3 from an unspecified species.	BIND	12810700
VEGFC	Flt4-L \| VRP	vascular endothelial growth factor C	-	HPRD,BioGRID	8700872

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-505	656	662	m8	hsa-miR-505	GUCAACACUUGCUGGUUUCCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.