Gene Page: FBXW11

Summary
GeneID  23291
Symbol  FBXW11
Synonyms  BTRC2|BTRCP2|FBW1B|FBXW1B|Fbw11|Hos|KIAA0696
Description  F-box and WD repeat domain containing 11
See related  HGNC:13607|MIM:605651|Ensembl:ENSG00000072803|HPRD:07294|
Locus tag  -
Gene type  protein-coding
Map location  5q35.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI15070733 |17353931 
GO:0004842ubiquitin-protein ligase activityNAS10531035 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006511ubiquitin-dependent protein catabolic processIEA-
GO:0016055Wnt receptor signaling pathwayIEA-
GO:0016567protein ubiquitinationNAS10531035 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000151ubiquitin ligase complexNAS10531035 
GO:0005737cytoplasmIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BTRCBETA-TRCP | FBW1A | FBXW1 | FBXW1A | FWD1 | MGC4643 | bTrCP | bTrCP1 | betaTrCPbeta-transducin repeat containing-HPRD,BioGRID10644755 
CDC25ACDC25A2cell division cycle 25 homolog A (S. pombe)-HPRD14603323 
CUL1MGC149834 | MGC149835cullin 1Affinity Capture-WesternBioGRID10644755 
CUL7KIAA0076 | dJ20C7.5cullin 7-HPRD12481031 
FBXW11BTRC2 | BTRCP2 | FBW1B | FBXW1B | Fbw11 | Hos | KIAA0696F-box and WD repeat domain containing 11-HPRD,BioGRID10644755 
NFKBIAIKBA | MAD-3 | NFKBInuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha-HPRD,BioGRID10644755 
RPRMFLJ90327 | REPRIMOreprimo, TP53 dependent G2 arrest mediator candidateAffinity Capture-MSBioGRID17353931 
SKP1EMC19 | MGC34403 | OCP-II | OCP2 | SKP1A | TCEB1L | p19AS-phase kinase-associated protein 1Affinity Capture-WesternBioGRID10644755 
WEE1DKFZp686I18166 | FLJ16446 | WEE1A | WEE1huWEE1 homolog (S. pombe)Wee1A interacts with an unspecified isoform of beta-TrCP2.BIND15070733 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-10123982404m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-133162216281Ahsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-1447537601A,m8hsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-150208220891A,m8hsa-miR-150UCUCCCAACCCUUGUACCAGUG
miR-17-5p/20/93.mr/106/519.d713m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-18223132319m8hsa-miR-182UUUGGCAAUGGUAGAACUCACA
hsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-200bc/429924930m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-21724892495m8hsa-miR-217UACUGCAUCAGGAACUGAUUGGAU
miR-331214321491Ahsa-miR-331brainGCCCCUGGGCCUAUCCUAGAA
miR-369-3p24842490m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-44821032109m8hsa-miR-448UUGCAUAUGUAGGAUGUCCCAU
miR-9158915951Ahsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
miR-964214281A,m8hsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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