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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: FNTA

Summary

GeneID

2339

Symbol

FNTA

Synonyms

FPTA|MGC99680|PGGT1A|PTAR2

Description

farnesyltransferase, CAAX box, alpha

Locus tag

Gene type

protein-coding

Map location

8p11

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

NTRK3

0.57

0.60

UNC13B

0.57

0.58

MON1B

0.56

0.54

KCTD1

0.55

0.69

TMEM201

0.54

0.52

APBA2

0.54

0.55

SIK2

0.54

0.63

DMRT3

0.54

0.47

IKZF2

0.54

0.41

PHLDA1

0.53

0.44

Top 10 negatively co-expressed genes

AL139819.3

-0.34

-0.38

AF347015.21

-0.32

-0.27

SYCP3

-0.32

-0.38

C1orf54

-0.31

-0.33

GNG11

-0.31

RHOC

-0.30

-0.37

DBI

-0.30

-0.38

MTERFD3

-0.30

-0.35

AF347015.31

-0.29

-0.21

IL32

-0.29

-0.34

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

15170324 |17353931

GO:0004660

protein farnesyltransferase activity

TAS

8276393

GO:0004662

CAAX-protein geranylgeranyltransferase activity

IEA

GO:0016740

transferase activity

IEA

GO:0030548

acetylcholine receptor regulator activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0045213

neurotransmitter receptor metabolic process

IEA

Synap, Neurotransmitter (GO term level: 7)

GO:0007179

transforming growth factor beta receptor signaling pathway

TAS

8599089

GO:0018347

protein amino acid farnesylation

TAS

8494894

GO:0018348

protein amino acid geranylgeranylation

TAS

8106351

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005829

cytosol

EXP

11313965

GO:0005737

cytoplasm

TAS

8599089

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACVR1	ACTRI \| ACVR1A \| ACVRLK2 \| ALK2 \| FOP \| SKR1 \| TSRI	activin A receptor, type I	-	HPRD,BioGRID	8599089
FNTB	FPTB \| MGC31935	farnesyltransferase, CAAX box, beta	-	HPRD	12825937
PTP4A2	HH13 \| HH7-2 \| HU-PP-1 \| OV-1 \| PRL-2 \| PRL2 \| PTP4A \| PTPCAAX2 \| ptp-IV1a \| ptp-IV1b	protein tyrosine phosphatase type IVA, member 2	Affinity Capture-MS	BioGRID	17353931
TGFB1	CED \| DPD1 \| TGFB \| TGFbeta	transforming growth factor, beta 1	-	HPRD,BioGRID	8599089
TGFBR1	AAT5 \| ACVRLK4 \| ALK-5 \| ALK5 \| LDS1A \| LDS2A \| SKR4 \| TGFR-1	transforming growth factor, beta receptor 1	-	HPRD,BioGRID	8530343

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-182	458	464	1A	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-409-5p	446	452	1A	hsa-miR-409-5p	AGGUUACCCGAGCAACUUUGCA
miR-96	458	464	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.