Gene Page

Gene Page: ITGB3BP

Summary

GeneID

23421

Symbol

ITGB3BP

Synonyms

CENP-R|CENPR|HSU37139|NRIF3|TAP20

Description

integrin beta 3 binding protein (beta3-endonexin)

Locus tag

Gene type

protein-coding

Map location

1p31.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_IIA

genome scan meta-analysis (All samples)

Psr: 0.02692

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004871

signal transducer activity

TAS

10490654

GO:0008022

protein C-terminus binding

TAS

10490654

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0007155

cell adhesion

TAS

7593198

GO:0006350

transcription

IEA

GO:0007165

signal transduction

TAS

7593198 |10490654

GO:0006915

apoptosis

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000775

chromosome, centromeric region

IEA

GO:0005624

membrane fraction

TAS

7593198

GO:0005634

nucleus

TAS

10490654

GO:0005694

chromosome

IEA

GO:0005737

cytoplasm

TAS

7593198

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ARFIP2	POR1	ADP-ribosylation factor interacting protein 2	Two-hybrid	BioGRID	16189514
CCNA2	CCN1 \| CCNA	cyclin A2	-	HPRD,BioGRID	10673397
COL4A3BP	CERT \| CERTL \| FLJ20597 \| GPBP \| STARD11	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	Two-hybrid	BioGRID	16189514
DDX24	-	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	Two-hybrid	BioGRID	16169070
ITGB3	CD61 \| GP3A \| GPIIIa	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	-	HPRD,BioGRID	7593198 \|11864709
ITGB3BP	CENP-R \| CENPR \| HSU37139 \| NRIF3 \| TAP20	integrin beta 3 binding protein (beta3-endonexin)	-	HPRD,BioGRID	11713274
ITGB5	FLJ26658	integrin, beta 5	in vivo	BioGRID	10579726
MTA1	-	metastasis associated 1	MTA1 interacts with NRIF3.	BIND	15254226
NFKB1	DKFZp686C01211 \| EBP-1 \| KBF1 \| MGC54151 \| NF-kappa-B \| NFKB-p105 \| NFKB-p50 \| p105	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	-	HPRD,BioGRID	12244126
RECQL5	FLJ90603 \| RECQ5	RecQ protein-like 5	Two-hybrid	BioGRID	16169070
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	-	HPRD,BioGRID	12244126
RXRA	FLJ00280 \| FLJ00318 \| FLJ16020 \| FLJ16733 \| MGC102720 \| NR2B1	retinoid X receptor, alpha	-	HPRD,BioGRID	10490654
RXRG	NR2B3 \| RXRC	retinoid X receptor, gamma	Two-hybrid	BioGRID	11713274
THRA	AR7 \| EAR7 \| ERB-T-1 \| ERBA \| ERBA1 \| MGC000261 \| MGC43240 \| NR1A1 \| THRA1 \| THRA2 \| c-ERBA-1	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	Reconstituted Complex Two-hybrid	BioGRID	10490654 \|11713274

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-151	132	138	1A	hsa-miR-151^brain	ACUAGACUGAAGCUCCUUGAGG
miR-203.1	204	210	m8	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-22	150	156	1A	hsa-miR-22^brain	AAGCUGCCAGUUGAAGAACUGU
miR-496	193	199	1A	hsa-miR-496	AUUACAUGGCCAAUCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.