Gene Page: HCG27
Summary ?
| GeneID | 253018 |
| Symbol | HCG27 |
| Synonyms | bCX101P6.9|bPG299F13.9|bQB115I13.2 |
| Description | HLA complex group 27 (non-protein coding) |
| Reference | HGNC:HGNC:27366|Ensembl:ENSG00000206344|HPRD:13637|Vega:OTTHUMG00000031248 |
| Gene type | ncRNA |
| Map location | 6p21.33 |
| Pascal p-value | 1E-12 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_I | Genome scan meta-analysis | Psr: 0.033 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| snp_a-2120929 | 0 | HCG27 | 253018 | 0.04 | trans | |||
| rs17572651 | chr1 | 218943612 | HCG27 | 253018 | 0.08 | trans | ||
| rs13214471 | chr6 | 38965864 | HCG27 | 253018 | 0.19 | trans | ||
| rs16955618 | chr15 | 29937543 | HCG27 | 253018 | 0.01 | trans | ||
| snp_a-1830894 | 0 | HCG27 | 253018 | 0.07 | trans | |||
| rs4713443 | 6 | 31155539 | HCG27 | ENSG00000206344.6 | 3.331E-7 | 0 | -9998 | gtex_brain_putamen_basal |
| rs4713444 | 6 | 31155548 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -9989 | gtex_brain_putamen_basal |
| rs7755428 | 6 | 31158385 | HCG27 | ENSG00000206344.6 | 2.063E-7 | 0 | -7152 | gtex_brain_putamen_basal |
| rs7741806 | 6 | 31158786 | HCG27 | ENSG00000206344.6 | 2.256E-7 | 0 | -6751 | gtex_brain_putamen_basal |
| rs7764668 | 6 | 31159630 | HCG27 | ENSG00000206344.6 | 1.398E-7 | 0 | -5907 | gtex_brain_putamen_basal |
| rs4711259 | 6 | 31161176 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -4361 | gtex_brain_putamen_basal |
| rs7762933 | 6 | 31162520 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -3017 | gtex_brain_putamen_basal |
| rs4713446 | 6 | 31162839 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -2698 | gtex_brain_putamen_basal |
| rs4713447 | 6 | 31162963 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -2574 | gtex_brain_putamen_basal |
| rs7743722 | 6 | 31163106 | HCG27 | ENSG00000206344.6 | 3.598E-7 | 0 | -2431 | gtex_brain_putamen_basal |
| rs9500882 | 6 | 31164549 | HCG27 | ENSG00000206344.6 | 5.563E-7 | 0 | -988 | gtex_brain_putamen_basal |
| rs28362333 | 6 | 31164779 | HCG27 | ENSG00000206344.6 | 6.408E-7 | 0 | -758 | gtex_brain_putamen_basal |
| rs28362335 | 6 | 31164849 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -688 | gtex_brain_putamen_basal |
| rs28362336 | 6 | 31164901 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -636 | gtex_brain_putamen_basal |
| rs9500883 | 6 | 31165100 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | -437 | gtex_brain_putamen_basal |
| rs9501075 | 6 | 31165177 | HCG27 | ENSG00000206344.6 | 3.749E-7 | 0 | -360 | gtex_brain_putamen_basal |
| rs28362342 | 6 | 31165438 | HCG27 | ENSG00000206344.6 | 1.026E-7 | 0 | -99 | gtex_brain_putamen_basal |
| rs28362345 | 6 | 31165836 | HCG27 | ENSG00000206344.6 | 9.686E-8 | 0 | 299 | gtex_brain_putamen_basal |
| rs9404980 | 6 | 31166297 | HCG27 | ENSG00000206344.6 | 1.443E-6 | 0 | 760 | gtex_brain_putamen_basal |
| rs9404981 | 6 | 31166378 | HCG27 | ENSG00000206344.6 | 3.31E-7 | 0 | 841 | gtex_brain_putamen_basal |
| rs9404982 | 6 | 31166539 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | 1002 | gtex_brain_putamen_basal |
| rs9468891 | 6 | 31167170 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | 1633 | gtex_brain_putamen_basal |
| rs9501077 | 6 | 31167512 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | 1975 | gtex_brain_putamen_basal |
| rs3868075 | 6 | 31167815 | HCG27 | ENSG00000206344.6 | 3.318E-7 | 0 | 2278 | gtex_brain_putamen_basal |
| rs9366768 | 6 | 31168494 | HCG27 | ENSG00000206344.6 | 3.053E-7 | 0 | 2957 | gtex_brain_putamen_basal |
| rs9380224 | 6 | 31168676 | HCG27 | ENSG00000206344.6 | 2.989E-7 | 0 | 3139 | gtex_brain_putamen_basal |
| rs10947144 | 6 | 31168777 | HCG27 | ENSG00000206344.6 | 4.351E-7 | 0 | 3240 | gtex_brain_putamen_basal |
| rs200364401 | 6 | 31168865 | HCG27 | ENSG00000206344.6 | 2.749E-7 | 0 | 3328 | gtex_brain_putamen_basal |
| . | 6 | 31168867 | HCG27 | ENSG00000206344.6 | 2.274E-7 | 0 | 3330 | gtex_brain_putamen_basal |
| rs9295962 | 6 | 31169438 | HCG27 | ENSG00000206344.6 | 2.973E-7 | 0 | 3901 | gtex_brain_putamen_basal |
| rs9295963 | 6 | 31169494 | HCG27 | ENSG00000206344.6 | 2.528E-7 | 0 | 3957 | gtex_brain_putamen_basal |
| rs9295964 | 6 | 31169538 | HCG27 | ENSG00000206344.6 | 1.931E-7 | 0 | 4001 | gtex_brain_putamen_basal |
| rs9366770 | 6 | 31170228 | HCG27 | ENSG00000206344.6 | 7.885E-8 | 0 | 4691 | gtex_brain_putamen_basal |
| rs9263871 | 6 | 31170528 | HCG27 | ENSG00000206344.6 | 2.319E-8 | 0 | 4991 | gtex_brain_putamen_basal |
| rs9263872 | 6 | 31170608 | HCG27 | ENSG00000206344.6 | 3.299E-7 | 0 | 5071 | gtex_brain_putamen_basal |
| rs9263873 | 6 | 31170713 | HCG27 | ENSG00000206344.6 | 3.299E-7 | 0 | 5176 | gtex_brain_putamen_basal |
| rs6930065 | 6 | 31173669 | HCG27 | ENSG00000206344.6 | 5.84E-9 | 0 | 8132 | gtex_brain_putamen_basal |
| rs6936604 | 6 | 31174926 | HCG27 | ENSG00000206344.6 | 5.675E-9 | 0 | 9389 | gtex_brain_putamen_basal |
| rs6919603 | 6 | 31175912 | HCG27 | ENSG00000206344.6 | 1.063E-7 | 0 | 10375 | gtex_brain_putamen_basal |
| rs41268852 | 6 | 31222369 | HCG27 | ENSG00000206344.6 | 1.511E-6 | 0 | 56832 | gtex_brain_putamen_basal |
| rs11968046 | 6 | 31302642 | HCG27 | ENSG00000206344.6 | 7.211E-7 | 0 | 137105 | gtex_brain_putamen_basal |
| rs6919086 | 6 | 31302927 | HCG27 | ENSG00000206344.6 | 1.876E-7 | 0 | 137390 | gtex_brain_putamen_basal |
| rs35918006 | 6 | 31308983 | HCG27 | ENSG00000206344.6 | 1.169E-6 | 0 | 143446 | gtex_brain_putamen_basal |
| rs545261677 | 6 | 31312458 | HCG27 | ENSG00000206344.6 | 6.41E-7 | 0 | 146921 | gtex_brain_putamen_basal |
| rs12173764 | 6 | 31314012 | HCG27 | ENSG00000206344.6 | 6.284E-7 | 0 | 148475 | gtex_brain_putamen_basal |
| rs34707463 | 6 | 31315223 | HCG27 | ENSG00000206344.6 | 1.484E-6 | 0 | 149686 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| OSMAN BLADDER CANCER DN | 406 | 230 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |