Gene Page: APEX2

Summary
GeneID  27301
Symbol  APEX2
Synonyms  APE2|APEXL2|XTH2
Description  APEX nuclease (apurinic/apyrimidinic endonuclease) 2
See related  HGNC:17889|Ensembl:ENSG00000169188|HPRD:06442|
Locus tag  RP5-884M20.3
Gene type  protein-coding
Map location  Xp11.21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0003906DNA-(apurinic or apyrimidinic site) lyase activityIEA-
GO:0004519endonuclease activityIEA-
GO:0016829lyase activityIEA-
GO:0008270zinc ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006281DNA repairIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIEA-
GO:0005739mitochondrionIEA-
GO:0005743mitochondrial inner membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALCOCO2MGC17318 | NDP52calcium binding and coiled-coil domain 2Two-hybridBioGRID16189514 
CCDC85BDIPAcoiled-coil domain containing 85BTwo-hybridBioGRID16189514 
EFEMP2FBLN4 | MBP1 | UPH1EGF-containing fibulin-like extracellular matrix protein 2Two-hybridBioGRID16189514 
HOOK2FLJ26218 | HK2hook homolog 2 (Drosophila)Two-hybridBioGRID16189514 
PCNAMGC8367proliferating cell nuclear antigen-HPRD,BioGRID11376153 
APE2 is a PCNA-binding proteinBIND11376153 
RP4-691N24.1FLJ11792 | KIAA0980 | NLP | dJ691N24.1ninein-likeTwo-hybridBioGRID16189514 
TRAF2MGC:45012 | TRAP | TRAP3TNF receptor-associated factor 2Two-hybridBioGRID16189514 
TRIM37KIAA0898 | MUL | POB1 | TEF3tripartite motif-containing 37Two-hybridBioGRID16189514 
 


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