Gene Page: ANGPTL3

Summary
GeneID  27329
Symbol  ANGPTL3
Synonyms  ANGPT5
Description  angiopoietin-like 3
See related  HGNC:491|MIM:604774|Ensembl:ENSG00000132855|HPRD:10381|
Locus tag  -
Gene type  protein-coding
Map location  1p31.1-p22.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02692 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005178integrin bindingIPI11877390 
GO:0004859phospholipase inhibitor activityIDA17110602 
GO:0004857enzyme inhibitor activityISS-
GO:0008083growth factor activityIDA11877390 
GO:0043498cell surface bindingIDA12565906 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007160cell-matrix adhesionIPI11877390 
GO:0007229integrin-mediated signaling pathwayNAS11877390 
GO:0006071glycerol metabolic processIDA12565906 
GO:0007165signal transductionIEA-
GO:0008203cholesterol metabolic processIDA17110602 
GO:0009395phospholipid catabolic processIDA17110602 
GO:0010519negative regulation of phospholipase activityIDA17110602 
GO:0019915sequestering of lipidIDA12565906 
GO:0006631fatty acid metabolic processIDA12565906 
GO:0051005negative regulation of lipoprotein lipase activityIDA17110602 
GO:0030335positive regulation of cell migrationIDA11877390 
GO:0050996positive regulation of lipid catabolic processIDA12565906 
GO:0042632cholesterol homeostasisIDA17110602 
GO:0045766positive regulation of angiogenesisIDA11877390 
GO:0048844artery morphogenesisIEA-
GO:0055090acylglycerol homeostasisIDA17110602 
GO:0055091phospholipid homeostasisIDA17110602 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceIDA17110602 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ITGA5CD49e | FNRA | VLA5Aintegrin, alpha 5 (fibronectin receptor, alpha polypeptide)-HPRD11877390 
ITGAVCD51 | DKFZp686A08142 | MSK8 | VNRAintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)-HPRD11877390 
ITGB3CD61 | GP3A | GPIIIaintegrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)-HPRD11877390 
 


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