Gene Page: GOT1

Summary
GeneID  2805
Symbol  GOT1
Synonyms  GIG18
Description  glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
See related  HGNC:4432|MIM:138180|Ensembl:ENSG00000120053|HPRD:00687|
Locus tag  -
Gene type  protein-coding
Map location  10q24.1-q25.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ENTPD40.820.88
ARHGEF110.820.86
EIF4G30.810.87
USP310.800.86
SENP50.790.85
ARHGEF70.780.87
ADAT10.780.85
UBE4A0.780.85
MAP3K130.780.86
VPS530.780.85
Top 10 negatively co-expressed genes
AF347015.31-0.62-0.70
AF347015.21-0.62-0.72
MT-CO2-0.59-0.68
AF347015.8-0.59-0.67
FXYD1-0.59-0.65
CST3-0.58-0.67
HIGD1B-0.58-0.69
APOE-0.58-0.67
S100A16-0.58-0.65
METRN-0.57-0.67
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004069aspartate transaminase activityEXPglutamate (GO term level: 6)2241899 
GO:0004069aspartate transaminase activityIDAglutamate (GO term level: 6)2182221 |2241899 |2731362 
|6391741 
GO:0030170pyridoxal phosphate bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006520amino acid metabolic processIEA-
GO:0006533aspartate catabolic processIDA2241899 
GO:0009058biosynthetic processIEA-
GO:0032869cellular response to insulin stimulusIEP8396422 
GO:0051384response to glucocorticoid stimulusIEP8396422 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP2241899 
GO:0005737cytoplasmIDA7060339 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-92430m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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