Gene Page: GRB14

Summary
GeneID  2888
Symbol  GRB14
Synonyms  -
Description  growth factor receptor-bound protein 14
See related  HGNC:4565|MIM:601524|Ensembl:ENSG00000115290|HPRD:03313|
Locus tag  -
Gene type  protein-coding
Map location  2q22-q24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.02395 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
GPR37L10.920.91
SELENBP10.920.90
ACSBG10.920.90
SLC9A3R10.900.82
SLC25A180.890.89
SFXN50.880.86
SLC13A50.880.82
OAF0.870.89
MERTK0.850.84
GLUL0.850.85
Top 10 negatively co-expressed genes
FARSB-0.68-0.75
C6orf168-0.68-0.72
DYNC1LI1-0.67-0.74
UBE2D2-0.66-0.67
GNL3-0.66-0.79
HELQ-0.66-0.72
MED19-0.66-0.77
EIF4E2-0.66-0.75
SUPV3L1-0.66-0.79
PPP3CC-0.66-0.79
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005070SH3/SH2 adaptor activityTAS8647858 
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionTAS8647858 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005737cytoplasmIEA-
GO:0005768endosomeIEA-
GO:0016020membraneIEA-
GO:0010008endosome membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DAPK3FLJ36473 | ZIP | ZIPKdeath-associated protein kinase 3Reconstituted ComplexBioGRID12242277 
EGFRERBB | ERBB1 | HER1 | PIG61 | mENAepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)-HPRD,BioGRID8647858 
FGFR1BFGFR | CD331 | CEK | FGFBR | FLG | FLJ99988 | FLT2 | HBGFR | KAL2 | N-SAMfibroblast growth factor receptor 1-HPRD,BioGRID10713090 
FTCDLCHC1formiminotransferase cyclodeaminaseCo-fractionationBioGRID11278563 
INSRCD220 | HHF5insulin receptor-HPRD,BioGRID9748281 |11726652 
PDGFRACD140A | MGC74795 | PDGFR2 | Rhe-PDGFRAplatelet-derived growth factor receptor, alpha polypeptide-HPRD8647858 
PDGFRBCD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1platelet-derived growth factor receptor, beta polypeptide-HPRD,BioGRID8647858 
PRKCZPKC-ZETA | PKC2protein kinase C, zeta-HPRD,BioGRID12242277 
TEKCD202B | TIE-2 | TIE2 | VMCM | VMCM1TEK tyrosine kinase, endothelial-HPRD10521483 
TNKS2PARP-5b | PARP-5c | PARP5B | PARP5C | TANK2 | TNKLtankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2-HPRD,BioGRID11278563 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p1211271Ahsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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