Gene Page: GRLF1

Summary
GeneID  2909
Symbol  GRLF1
Synonyms  GRF-1|KIAA1722|MGC10745|P190-A|P190A|p190RhoGAP
Description  glucocorticoid receptor DNA binding factor 1
See related  HGNC:4591|MIM:605277|HPRD:05592|
Locus tag  -
Gene type  protein-coding
Map location  19q13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ARMCX30.920.89
VPS350.910.89
NARS0.910.89
NCKAP10.910.89
RANBP90.910.87
AKIRIN10.900.88
TRIM230.900.89
CLTC0.900.88
YWHAB0.900.88
DLD0.900.88
Top 10 negatively co-expressed genes
AF347015.21-0.67-0.52
MT-CO2-0.62-0.51
AF347015.8-0.61-0.51
HIGD1B-0.61-0.51
FXYD1-0.60-0.52
AF347015.18-0.60-0.53
AF347015.2-0.60-0.47
PLA2G5-0.60-0.54
AF347015.31-0.60-0.51
MT-CYB-0.58-0.48
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingTAS1894621 
GO:0003714transcription corepressor activityTAS1894621 
GO:0005096GTPase activator activityIEA-
GO:0005525GTP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030900forebrain developmentIEABrain (GO term level: 8)-
GO:0001843neural tube closureIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0007165signal transductionIEA-
GO:0008360regulation of cell shapeIEA-
GO:0007264small GTPase mediated signal transductionIEA-
GO:0016481negative regulation of transcriptionIDA1894621 
GO:0043010camera-type eye developmentIEA-
GO:0045786negative regulation of cell cycleIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
GO:0005634nucleusIC1894621 
GO:0005737cytoplasmIEA-
GO:0015629actin cytoskeletonIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2Affinity Capture-WesternBioGRID12441060 
RASA1CM-AVM | CMAVM | DKFZp434N071 | GAP | PKWS | RASA | RASGAP | p120GAP | p120RASGAPRAS p21 protein activator (GTPase activating protein) 1Reconstituted ComplexBioGRID9034330 
RHOAARH12 | ARHA | RHO12 | RHOH12ras homolog gene family, member AReconstituted ComplexBioGRID9548756 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-130/301827833m8hsa-miR-130abrainCAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrainCAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3pUAGUGCAAUAUUGCUUAUAGGGUUU
miR-142-5p324132471Ahsa-miR-142-5pCAUAAAGUAGAAAGCACUAC
miR-17-5p/20/93.mr/106/519.d8298361A,m8hsa-miR-17-5pCAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrainUAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106aAAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZUAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZCAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519dCAAAGUGCCUCCCUUUAGAGUGU
miR-38132163222m8hsa-miR-381UAUACAAGGGCAAGCUCUCUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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