Gene Page: GUCA1B

Summary
GeneID  2979
Symbol  GUCA1B
Synonyms  DKFZp686E1183|GCAP2|GUCA2
Description  guanylate cyclase activator 1B (retina)
See related  HGNC:4679|MIM:602275|Ensembl:ENSG00000112599|HPRD:03783|
Locus tag  RP1-139D8.1
Gene type  protein-coding
Map location  6p21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABCC120.610.54
EPHX40.560.49
PIGP0.550.40
STEAP10.550.44
SMYD20.540.58
TNFSF13B0.530.40
MPL0.530.42
SH3GLB20.530.49
CCK0.530.48
ATG70.530.52
Top 10 negatively co-expressed genes
SMTN-0.28-0.27
GPR125-0.28-0.24
SH3BP2-0.28-0.32
GLIS2-0.27-0.26
PDE9A-0.27-0.32
SEMA3F-0.26-0.30
SH2D2A-0.26-0.29
PKN1-0.26-0.26
FAM59B-0.26-0.24
C16orf88-0.26-0.17
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0008048calcium sensitive guanylate cyclase activator activityTAS1409606 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007267cell-cell signalingTAS1409606 
GO:0007168receptor guanylyl cyclase signaling pathwayTAS1327879 
GO:0007601visual perceptionIEA-
GO:0007589body fluid secretionTAS1327879 
GO:0050896response to stimulusIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GUCY2FCYGF | GC-F | GUC2DL | GUC2F | RETGC-2 | ROS-GC2guanylate cyclase 2F, retinal-HPRD9698373 
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4949309361Ahsa-miR-494brainUGAAACAUACACGGGAAACCUCUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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