Gene Page: ZNF354C
Summary ?
| GeneID | 30832 |
| Symbol | ZNF354C |
| Synonyms | KID3 |
| Description | zinc finger protein 354C |
| Reference | HGNC:HGNC:16736|HPRD:15785| |
| Gene type | protein-coding |
| Map location | 5q35 |
| Pascal p-value | 0.002 |
| eGene | Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_IIA | Genome scan meta-analysis (All samples) | Psr: 0.0276 |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SENP7 | 0.90 | 0.93 |
| ZNF528 | 0.90 | 0.91 |
| ZNF662 | 0.89 | 0.87 |
| C12orf35 | 0.89 | 0.92 |
| ZCCHC11 | 0.89 | 0.91 |
| ZNF559 | 0.89 | 0.90 |
| UBR5 | 0.89 | 0.92 |
| PDE7A | 0.89 | 0.89 |
| AC004017.1 | 0.88 | 0.87 |
| ZNF551 | 0.88 | 0.88 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AIFM3 | -0.65 | -0.75 |
| LHPP | -0.65 | -0.62 |
| HLA-F | -0.65 | -0.73 |
| FBXO2 | -0.65 | -0.68 |
| C5orf53 | -0.63 | -0.71 |
| AF347015.31 | -0.63 | -0.83 |
| PTH1R | -0.63 | -0.71 |
| IFI27 | -0.63 | -0.84 |
| AF347015.27 | -0.63 | -0.81 |
| S100B | -0.63 | -0.77 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0003677 | DNA binding | IEA | - | |
| GO:0008270 | zinc ion binding | IEA | - | |
| GO:0046872 | metal ion binding | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | - | |
| GO:0006350 | transcription | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005622 | intracellular | IEA | - | |
| GO:0005634 | nucleus | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME GENERIC TRANSCRIPTION PATHWAY | 352 | 181 | All SZGR 2.0 genes in this pathway |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |